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- W2122227850 abstract "Nine title compounds were synthesized and investigated in the Born test for their antiplatelet activities against collagen, ADP, adrenaline, and platelet activating factor (PAF) as inducers of the aggregation. Using collagen three compounds with IC50 values below 100 microM were found (3b, 3e, 3i). Activities in nanomolar concentrations were observed against ADP (3b, IC50 = 9.4 nM), adrenaline (3i, IC50 = 5.8 nM), and platelet activating factor (3e, IC50 = 0.45 nM)." @default.
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- W2122227850 date "2009-01-01" @default.
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- W2122227850 title "New 1<i>H</i>-Pyrazole-4-Carboxamides with Antiplatelet Activity" @default.
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- W2122227850 doi "https://doi.org/10.1002/ardp.200800181" @default.
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