FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2122287657> ?p ?o ?g. }

• W2122287657 endingPage "2771" @default.
• W2122287657 startingPage "2761" @default.
• W2122287657 abstract "Patients with recurrence after complete resection of colorectal liver metastases (CLM) are considered for repeat resection as a potential salvage therapy (PST). However, outcomes for this approach are not well defined. We sought to analyze the natural history of recurrence and PST in a large cohort of patients with long-term follow-up. Recurrence patterns, treatments, and outcomes in consecutive patients undergoing resection for colorectal liver metastases were analyzed retrospectively. PST was defined as repeat resection of all recurrent disease and effective salvage therapy (EST) as free of disease for 36 months after last PST. Factors associated with PST, EST, and outcomes were analyzed. Of 952 patients who underwent resection, 594 (62 %) experienced recurrence (median interval = 13 months). Initial recurrences involved liver (n = 157,26 %), lung (n = 167,28 %), multiple sites (n = 171,29 %), and other single sites (n = 99,17 %). PST was performed in 160 (27 %) of 594, most commonly with a single site of recurrence (n = 149). Young age (p = 0.01), negative initial resection margin (p = 0.003), initial tumor size <5 cm (p = 0.006), and recurrence pattern (p < 0.001) were independently associated with PST. Thirty-six patients experienced EST (25 % of PSTs). Overall median survival was 61 and 43 months in those with recurrence. Median survival of patients undergoing PST was 87 months compared to 34 months for those who did not. Recurrence is common after CLM resection, but 27 % of patients were able to undergo PST. Approximately one-quarter of these experienced EST and may be cured. PST is associated with long-term survival and possible cure, and therefore active surveillance after CLM resection is justified." @default.
• W2122287657 created "2016-06-24" @default.
• W2122287657 creator A5005824918 @default.
• W2122287657 creator A5009465403 @default.
• W2122287657 creator A5019093893 @default.
• W2122287657 creator A5021772683 @default.
• W2122287657 creator A5032338183 @default.
• W2122287657 creator A5036762729 @default.
• W2122287657 creator A5042440032 @default.
• W2122287657 creator A5051277222 @default.
• W2122287657 creator A5069644669 @default.
• W2122287657 creator A5078241870 @default.
• W2122287657 date "2015-01-09" @default.
• W2122287657 modified "2023-10-18" @default.
• W2122287657 title "Recurrence After Partial Hepatectomy for Metastatic Colorectal Cancer: Potentially Curative Role of Salvage Repeat Resection" @default.
• W2122287657 cites W1848603902 @default.
• W2122287657 cites W1971435361 @default.
• W2122287657 cites W1973923565 @default.
• W2122287657 cites W1973953362 @default.
• W2122287657 cites W1977863126 @default.
• W2122287657 cites W1981813030 @default.
• W2122287657 cites W1981860107 @default.
• W2122287657 cites W1982461820 @default.
• W2122287657 cites W1991448174 @default.
• W2122287657 cites W1993145793 @default.
• W2122287657 cites W2002260386 @default.
• W2122287657 cites W2004507999 @default.
• W2122287657 cites W2009123057 @default.
• W2122287657 cites W2015950544 @default.
• W2122287657 cites W2016242578 @default.
• W2122287657 cites W2026673439 @default.
• W2122287657 cites W2034430615 @default.
• W2122287657 cites W2035102087 @default.
• W2122287657 cites W2035133028 @default.
• W2122287657 cites W2047756678 @default.
• W2122287657 cites W2058069343 @default.
• W2122287657 cites W2059975503 @default.
• W2122287657 cites W2060216759 @default.
• W2122287657 cites W2063685444 @default.
• W2122287657 cites W2068670884 @default.
• W2122287657 cites W2084470612 @default.
• W2122287657 cites W2101815035 @default.
• W2122287657 cites W2167506886 @default.
• W2122287657 cites W2302000485 @default.
• W2122287657 cites W2568330612 @default.
• W2122287657 cites W4239365184 @default.
• W2122287657 doi "https://doi.org/10.1245/s10434-015-4370-1" @default.
• W2122287657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4780326" @default.
• W2122287657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25572686" @default.
• W2122287657 hasPublicationYear "2015" @default.
• W2122287657 type Work @default.
• W2122287657 sameAs 2122287657 @default.
• W2122287657 citedByCount "77" @default.
• W2122287657 countsByYear W21222876572015 @default.
• W2122287657 countsByYear W21222876572016 @default.
• W2122287657 countsByYear W21222876572017 @default.
• W2122287657 countsByYear W21222876572018 @default.
• W2122287657 countsByYear W21222876572019 @default.
• W2122287657 countsByYear W21222876572020 @default.
• W2122287657 countsByYear W21222876572021 @default.
• W2122287657 countsByYear W21222876572022 @default.
• W2122287657 countsByYear W21222876572023 @default.
• W2122287657 crossrefType "journal-article" @default.
• W2122287657 hasAuthorship W2122287657A5005824918 @default.
• W2122287657 hasAuthorship W2122287657A5009465403 @default.
• W2122287657 hasAuthorship W2122287657A5019093893 @default.
• W2122287657 hasAuthorship W2122287657A5021772683 @default.
• W2122287657 hasAuthorship W2122287657A5032338183 @default.
• W2122287657 hasAuthorship W2122287657A5036762729 @default.
• W2122287657 hasAuthorship W2122287657A5042440032 @default.
• W2122287657 hasAuthorship W2122287657A5051277222 @default.
• W2122287657 hasAuthorship W2122287657A5069644669 @default.
• W2122287657 hasAuthorship W2122287657A5078241870 @default.
• W2122287657 hasBestOaLocation W21222876572 @default.
• W2122287657 hasConcept C121608353 @default.
• W2122287657 hasConcept C126322002 @default.
• W2122287657 hasConcept C141071460 @default.
• W2122287657 hasConcept C159110652 @default.
• W2122287657 hasConcept C167135981 @default.
• W2122287657 hasConcept C2776694085 @default.
• W2122287657 hasConcept C2776909242 @default.
• W2122287657 hasConcept C2778132481 @default.
• W2122287657 hasConcept C2780140570 @default.
• W2122287657 hasConcept C2780775027 @default.
• W2122287657 hasConcept C526805850 @default.
• W2122287657 hasConcept C71924100 @default.
• W2122287657 hasConcept C72563966 @default.
• W2122287657 hasConcept C90924648 @default.
• W2122287657 hasConceptScore W2122287657C121608353 @default.
• W2122287657 hasConceptScore W2122287657C126322002 @default.
• W2122287657 hasConceptScore W2122287657C141071460 @default.
• W2122287657 hasConceptScore W2122287657C159110652 @default.
• W2122287657 hasConceptScore W2122287657C167135981 @default.
• W2122287657 hasConceptScore W2122287657C2776694085 @default.
• W2122287657 hasConceptScore W2122287657C2776909242 @default.
• W2122287657 hasConceptScore W2122287657C2778132481 @default.
• W2122287657 hasConceptScore W2122287657C2780140570 @default.
• W2122287657 hasConceptScore W2122287657C2780775027 @default.

• next