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- W2122290380 abstract "We herein report results of the first 8 patients with leukemia enrolled in a phase I study evaluating the safety and potential efficacy of cord blood (CB) progenitors cultured in the presence of the Notch ligand, Delta1. Following a myeloablative preparative regimen, patients received a CBU followed by a second unit that was expanded ex vivo. Median age and weight of the patients enrolled is 26 years (range 3 to 43) and 53 kg (16 to 76). After culture, the average CD34 fold increase was 135 (41 to 382) with an average total nucleated cell (TNC) fold increase of 570 (146 to 1496)." @default.
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- W2122290380 date "2009-02-01" @default.
- W2122290380 modified "2023-10-16" @default.
- W2122290380 title "Ex Vivo Expansion of Human Cord Blood Progenitor Cells with the Notch Ligand Delta1 Results in Rapid Myeloid Reconstitution In Vivo Following Myeloablative Cord Blood Transplantation" @default.
- W2122290380 doi "https://doi.org/10.1016/j.bbmt.2008.12.032" @default.
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