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• W2122348902 endingPage "1438" @default.
• W2122348902 startingPage "1438" @default.
• W2122348902 abstract "Extensive research on tea catechins, mainly (-)-epigallocatechin gallate, has shown numerous health promoting effects. However, various clinical studies demonstrated several issues associated with tea catechins which account for their poor systemic bioavailability. In order to improve pharmacological activity and bioavailability of natural tea catechins, two major strategies have been adopted to date which include synthesizing catechin analogs/prodrugs and the development of novel drug delivery systems. In this review, we provide a detailed account of novel synthetic analogs/prodrugs as well as novel drug delivery approaches used for natural tea catechins to make them therapeutically potent drug-like molecules." @default.
• W2122348902 created "2016-06-24" @default.
• W2122348902 creator A5019865541 @default.
• W2122348902 creator A5038504758 @default.
• W2122348902 creator A5050406201 @default.
• W2122348902 creator A5078867683 @default.
• W2122348902 date "2013-01-01" @default.
• W2122348902 modified "2023-09-25" @default.
• W2122348902 title "Catechin prodrugs and analogs: a new array of chemical entities with improved pharmacological and pharmacokinetic properties" @default.
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