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• W2122443512 abstract "Recent data suggests that treating patients with pancreatic cancer that express mutations in BRCA1, BRCA2, and PALB2 with chemotherapy which targets the DNA repair defect in these cells, such as platinum based therapies or PARPi [poly (ADP-ribose) polymerase inhibitor], may be more beneficial in these patients. Moreover, further data also indicates the promise of combining PARPi with conventional chemotherapy. Authors summarize the data related to PARPi in BRCA-associated pancreatic cancer that was presented at the annual meeting of ASCO 2014. Enrolment on a clinical trial for patients who fit these criteria should be encouraged." @default.
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• W2122443512 date "2014-07-28" @default.
• W2122443512 modified "2023-09-26" @default.
• W2122443512 title "PARP-inhibitors in BRCA-associated pancreatic cancer." @default.
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• W2122443512 doi "https://doi.org/10.6092/1590-8577/2690" @default.
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