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- W2122500500 abstract "In a multi-centre double-blind cross-over trial using the double-placebo technique, 55 patients with rheumatoid arthritis were treated for 10 days for each trial drug with ketoprofen (200 mg/day) and ibuprofen (1200 mg/day). Both drugs induced a clinically and statistically significant improvement of all the symptoms studied, except for pain at night during ibuprofen administration. Ketoprofen displayed a therapeutic efficacy significantly superior to ibuprofen in five out of the eight symptoms studied. Side-effects were recorded in 10 patients receiving ketoprofen (one patient withdrew because of heartburn) and in nine patients receiving ibuprofen." @default.
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- W2122500500 date "1979-01-01" @default.
- W2122500500 modified "2023-10-10" @default.
- W2122500500 title "A DOUBLE-BLIND CROSS-OVER EVALUATION OF KETOPROFEN (ORUDIS) AND IBUPROFEN IN THE MANAGEMENT OF RHEUMATOID ARTHRITIS" @default.
- W2122500500 doi "https://doi.org/10.1093/rheumatology/18.2.114" @default.
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