Matches in SemOpenAlex for { <https://semopenalex.org/work/W2122566973> ?p ?o ?g. }
- W2122566973 endingPage "562" @default.
- W2122566973 startingPage "551" @default.
- W2122566973 abstract "Attachment to mucosal surfaces is the initial event in the pathogenesis of the human foodborne pathogen Listeria monocytogenes. By use of comparative genomics, we identified a L. monocytogenes-specific gene, lapB, that encodes an LPXTG surface protein that is absent from nonpathogenic Listeria species. We showed that lapB expression is positively regulated by PrfA, the major transcriptional activator of the virulence genes of Listeria species, and is up-regulated in mouse spleens during infection. We demonstrated that LapB is an SrtA-anchored surface protein required for adhesion to and entry into mammalian cells and for virulence following intravenous or oral inoculation in mice. Our results highlight LapB as a new L. monocytogenes virulence adhesin with a function that is supported by its unique N-terminal domain through the probable interaction with a cellular receptor." @default.
- W2122566973 created "2016-06-24" @default.
- W2122566973 creator A5014984934 @default.
- W2122566973 creator A5030120520 @default.
- W2122566973 creator A5032761824 @default.
- W2122566973 creator A5039995206 @default.
- W2122566973 creator A5065170723 @default.
- W2122566973 creator A5069188872 @default.
- W2122566973 creator A5075414397 @default.
- W2122566973 date "2010-08-15" @default.
- W2122566973 modified "2023-09-24" @default.
- W2122566973 title "LapB, a Novel<i>Listeria monocytogenes</i>LPXTG Surface Adhesin, Required for Entry into Eukaryotic Cells and Virulence" @default.
- W2122566973 cites W1827851367 @default.
- W2122566973 cites W1943944420 @default.
- W2122566973 cites W1964562548 @default.
- W2122566973 cites W1971898521 @default.
- W2122566973 cites W1977141229 @default.
- W2122566973 cites W1978163337 @default.
- W2122566973 cites W1986103534 @default.
- W2122566973 cites W1993641741 @default.
- W2122566973 cites W2000106054 @default.
- W2122566973 cites W2001553481 @default.
- W2122566973 cites W2005476432 @default.
- W2122566973 cites W2009270582 @default.
- W2122566973 cites W2016923481 @default.
- W2122566973 cites W2017645771 @default.
- W2122566973 cites W2020083726 @default.
- W2122566973 cites W2026701302 @default.
- W2122566973 cites W2035752210 @default.
- W2122566973 cites W2043422770 @default.
- W2122566973 cites W2043961065 @default.
- W2122566973 cites W2051610804 @default.
- W2122566973 cites W2059206113 @default.
- W2122566973 cites W2075361277 @default.
- W2122566973 cites W2078739770 @default.
- W2122566973 cites W2079210333 @default.
- W2122566973 cites W2092576643 @default.
- W2122566973 cites W2101978350 @default.
- W2122566973 cites W2107993914 @default.
- W2122566973 cites W2111310696 @default.
- W2122566973 cites W2115896695 @default.
- W2122566973 cites W2116103187 @default.
- W2122566973 cites W2121788859 @default.
- W2122566973 cites W2121860020 @default.
- W2122566973 cites W2122365028 @default.
- W2122566973 cites W2128037586 @default.
- W2122566973 cites W2130248239 @default.
- W2122566973 cites W2130487625 @default.
- W2122566973 cites W2133546866 @default.
- W2122566973 cites W2133746705 @default.
- W2122566973 cites W2136163749 @default.
- W2122566973 cites W2152187506 @default.
- W2122566973 cites W2156546955 @default.
- W2122566973 cites W2157833701 @default.
- W2122566973 cites W2163237429 @default.
- W2122566973 cites W317788252 @default.
- W2122566973 doi "https://doi.org/10.1086/654880" @default.
- W2122566973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20617901" @default.
- W2122566973 hasPublicationYear "2010" @default.
- W2122566973 type Work @default.
- W2122566973 sameAs 2122566973 @default.
- W2122566973 citedByCount "67" @default.
- W2122566973 countsByYear W21225669732012 @default.
- W2122566973 countsByYear W21225669732013 @default.
- W2122566973 countsByYear W21225669732014 @default.
- W2122566973 countsByYear W21225669732015 @default.
- W2122566973 countsByYear W21225669732016 @default.
- W2122566973 countsByYear W21225669732017 @default.
- W2122566973 countsByYear W21225669732018 @default.
- W2122566973 countsByYear W21225669732019 @default.
- W2122566973 countsByYear W21225669732020 @default.
- W2122566973 countsByYear W21225669732021 @default.
- W2122566973 countsByYear W21225669732022 @default.
- W2122566973 countsByYear W21225669732023 @default.
- W2122566973 crossrefType "journal-article" @default.
- W2122566973 hasAuthorship W2122566973A5014984934 @default.
- W2122566973 hasAuthorship W2122566973A5030120520 @default.
- W2122566973 hasAuthorship W2122566973A5032761824 @default.
- W2122566973 hasAuthorship W2122566973A5039995206 @default.
- W2122566973 hasAuthorship W2122566973A5065170723 @default.
- W2122566973 hasAuthorship W2122566973A5069188872 @default.
- W2122566973 hasAuthorship W2122566973A5075414397 @default.
- W2122566973 hasBestOaLocation W21225669731 @default.
- W2122566973 hasConcept C104317684 @default.
- W2122566973 hasConcept C179470777 @default.
- W2122566973 hasConcept C2776460866 @default.
- W2122566973 hasConcept C2778682378 @default.
- W2122566973 hasConcept C2781350384 @default.
- W2122566973 hasConcept C523546767 @default.
- W2122566973 hasConcept C54355233 @default.
- W2122566973 hasConcept C60987743 @default.
- W2122566973 hasConcept C86803240 @default.
- W2122566973 hasConcept C89423630 @default.
- W2122566973 hasConceptScore W2122566973C104317684 @default.
- W2122566973 hasConceptScore W2122566973C179470777 @default.
- W2122566973 hasConceptScore W2122566973C2776460866 @default.
- W2122566973 hasConceptScore W2122566973C2778682378 @default.
- W2122566973 hasConceptScore W2122566973C2781350384 @default.