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• W2122642664 startingPage "1170" @default.
• W2122642664 abstract "The mcrBDCGA operon that encodes methyl coenzyme M reductase (MR) in the hyperthermophile Methanopyrus kandleri was cloned and sequenced. The results of a phylogenetic analysis of the nine MR sequences now available support the position that M. kandleri is a separate methanogen lineage. As in other methanogens, the M. kandleri mcr operon is located immediately upstream of the mtrE gene, the promoter-proximal gene in an operon that encodes the N 5-methyltetrahydromethanopterin:coenzyme M methyltransferase that catalyzes the step preceding the MR-catalyzed reaction in methanogenesis. In contrast to other methanogens and hyperthermophilic members of the Archaea. CG dinucleotides and CG-containing codons occur frequently in M. kandleri DNA. The MR subunit-encoding genes are preceded by sequences consistent with ribosome binding sites, indicating that mRNA-rRNA base pairing can still direct translation initiation in cells growing at temperatures above 100°C." @default.
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• W2122642664 date "1996-10-01" @default.
• W2122642664 modified "2023-10-03" @default.
• W2122642664 title "NOTES: Phylogeny of Methanopyrus kandleri Based on Methyl Coenzyme M Reductase Operons" @default.
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• W2122642664 doi "https://doi.org/10.1099/00207713-46-4-1170" @default.
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