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- W2122700244 abstract "Picornaviruses that infect humans form one of the largest virus groups with almost three hundred virus types. They include significant enteroviral pathogens such as rhino-, polio-, echo-, and coxsackieviruses and human parechoviruses that cause wide range of disease symptoms. Despite the economic importance of picornaviruses, there are no antivirals. More than ten cellular receptors are known to participate in picornavirus infection, but experimental evidence of their role in cellular infection has been shown for only about twenty picornavirus types. Three enterovirus types and one parechovirus have experimentally been shown to bind and use integrin receptors in cellular infection. These include coxsackievirus A9 (CV-A9), echovirus 9, and human parechovirus 1 that are among the most common and epidemic human picornaviruses and bind to α V-integrins via RGD motif that resides on virus capsid. In contrast, echovirus 1 (E-1) has no RGD and uses integrin α 2 β 1 as cellular receptor. Endocytosis of CV-A9 has recently been shown to occur via a novel Arf6- and dynamin-dependent pathways, while, contrary to collagen binding, E-1 binds inactive β 1 integrin and enters via macropinocytosis. In this paper, we review what is known about receptors and endocytosis of integrin-binding human picornaviruses." @default.
- W2122700244 created "2016-06-24" @default.
- W2122700244 creator A5001426669 @default.
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- W2122700244 creator A5045682304 @default.
- W2122700244 creator A5052626959 @default.
- W2122700244 date "2012-01-01" @default.
- W2122700244 modified "2023-10-15" @default.
- W2122700244 title "Endocytosis of Integrin-Binding Human Picornaviruses" @default.
- W2122700244 cites W1490760691 @default.
- W2122700244 cites W1575798288 @default.
- W2122700244 cites W1576773659 @default.
- W2122700244 cites W1614227186 @default.
- W2122700244 cites W1774068000 @default.
- W2122700244 cites W1878933038 @default.
- W2122700244 cites W1908524553 @default.
- W2122700244 cites W1930673809 @default.
- W2122700244 cites W1951621827 @default.
- W2122700244 cites W1964115999 @default.
- W2122700244 cites W1966022051 @default.
- W2122700244 cites W1969025660 @default.
- W2122700244 cites W1969849192 @default.
- W2122700244 cites W1974478155 @default.
- W2122700244 cites W1977368737 @default.
- W2122700244 cites W1978315083 @default.
- W2122700244 cites W1982398946 @default.
- W2122700244 cites W1987568997 @default.
- W2122700244 cites W1991613172 @default.
- W2122700244 cites W1992285222 @default.
- W2122700244 cites W1996006630 @default.
- W2122700244 cites W1996453362 @default.
- W2122700244 cites W2001627863 @default.
- W2122700244 cites W2015704490 @default.
- W2122700244 cites W2018000717 @default.
- W2122700244 cites W2018009812 @default.
- W2122700244 cites W2020733401 @default.
- W2122700244 cites W2024600235 @default.
- W2122700244 cites W2025804775 @default.
- W2122700244 cites W2027292195 @default.
- W2122700244 cites W2027682791 @default.
- W2122700244 cites W2031805365 @default.
- W2122700244 cites W2047157488 @default.
- W2122700244 cites W2047204461 @default.
- W2122700244 cites W2048731695 @default.
- W2122700244 cites W2051245442 @default.
- W2122700244 cites W2051881371 @default.
- W2122700244 cites W2052664316 @default.
- W2122700244 cites W2055511881 @default.
- W2122700244 cites W2060073882 @default.
- W2122700244 cites W2061589432 @default.
- W2122700244 cites W2062452684 @default.
- W2122700244 cites W2065692062 @default.
- W2122700244 cites W2072378172 @default.
- W2122700244 cites W2074116391 @default.
- W2122700244 cites W2074858827 @default.
- W2122700244 cites W2076121001 @default.
- W2122700244 cites W2077326100 @default.
- W2122700244 cites W2084033845 @default.
- W2122700244 cites W2085437402 @default.
- W2122700244 cites W2086958200 @default.
- W2122700244 cites W2087591542 @default.
- W2122700244 cites W2091599508 @default.
- W2122700244 cites W2092019188 @default.
- W2122700244 cites W2095022596 @default.
- W2122700244 cites W2098846419 @default.
- W2122700244 cites W2101244168 @default.
- W2122700244 cites W2103977415 @default.
- W2122700244 cites W2104828313 @default.
- W2122700244 cites W2105761456 @default.
- W2122700244 cites W2107533173 @default.
- W2122700244 cites W2111209944 @default.
- W2122700244 cites W2112032807 @default.
- W2122700244 cites W2114286636 @default.
- W2122700244 cites W2116071714 @default.
- W2122700244 cites W2117130284 @default.
- W2122700244 cites W2121351192 @default.
- W2122700244 cites W2122412982 @default.
- W2122700244 cites W2130828052 @default.
- W2122700244 cites W2131388419 @default.
- W2122700244 cites W2132403603 @default.
- W2122700244 cites W2134851007 @default.
- W2122700244 cites W2137960852 @default.
- W2122700244 cites W2138623102 @default.
- W2122700244 cites W2139319426 @default.
- W2122700244 cites W2139436990 @default.
- W2122700244 cites W2140456056 @default.
- W2122700244 cites W2141612972 @default.
- W2122700244 cites W2141866534 @default.
- W2122700244 cites W2146130527 @default.
- W2122700244 cites W2147698215 @default.
- W2122700244 cites W2151752783 @default.
- W2122700244 cites W2157963288 @default.
- W2122700244 cites W2158900785 @default.
- W2122700244 cites W2160166947 @default.
- W2122700244 cites W2160913295 @default.
- W2122700244 cites W2162318638 @default.
- W2122700244 cites W2163065284 @default.