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- W2122752125 abstract "Staging mechanical properties of deep vein thrombi (elasticity and viscosity) can be of importance for therapy planning because the compactness of a blood clot impacts the efficiency of thrombolysis drugs. This article proposes the dynamic vascular elastography (DVE) method to solve this problem. It consists to retrieve viscoelastic parameters of 8-mm diameter blood clot cylindrical inclusions from shear wave propagation characteristics. The technique firstly implies the generation of a low frequency (50-190 Hz) harmonic plane shear wave in the medium and the tracking of this wave with an ultra- fast ultrasound scanner (frame rate > 3000 Hz). An inverse problem was formulated as a least-square minimization between simulations and experimental results of viscoelasticity. The wave excitation technique also permitted to do a multi-frequency analysis to validate the Voigt's model as a valid approach to represent the viscoelasticity of blood clots. DVE proved to have sufficient sensitivity to follow the time-varying blood coagulation process and to differentiate mechanical properties of blood samples with different hematocrits." @default.
- W2122752125 created "2016-06-24" @default.
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- W2122752125 date "2007-10-01" @default.
- W2122752125 modified "2023-10-01" @default.
- W2122752125 title "11C-5 Characterization of Time-Varying Mechanical Viscoelastic Parameters of Mimicking Deep Vein Thrombi with 2D Dynamic Elastography" @default.
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- W2122752125 doi "https://doi.org/10.1109/ultsym.2007.257" @default.
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