Matches in SemOpenAlex for { <https://semopenalex.org/work/W2122877> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2122877 abstract "Accurate tRNA processing is crucial for human mitochondrial genome expression, but the mechanisms and key enzymes involved are poorly characterized. Here we demonstrate for the first time that human protein ELAC2 localizes both in mitochondria and the nucleus. Using the RNAi gene silencing in HeLa cells we show that the ELAC2 gene encodes tRNAseZ endonuclease which is responsible for the mitochondrial tRNA 3' processing in vivo. In addition we demonstrate that the order of precursor cleavage in mitochondria follows the rule that tRNase Z can only cleave molecules already processed by RNase P." @default.
- W2122877 created "2016-06-24" @default.
- W2122877 creator A5025997398 @default.
- W2122877 creator A5050475672 @default.
- W2122877 creator A5057557326 @default.
- W2122877 creator A5086051241 @default.
- W2122877 date "2011-07-01" @default.
- W2122877 modified "2023-10-16" @default.
- W2122877 title "Human ELAC2 gene encodes the tRNAseZ responsible for mitochondrial tRNA 3’ processing which acts on precursors already cleaved by RNAseP" @default.
- W2122877 hasPublicationYear "2011" @default.
- W2122877 type Work @default.
- W2122877 sameAs 2122877 @default.
- W2122877 citedByCount "2" @default.
- W2122877 countsByYear W21228772012 @default.
- W2122877 countsByYear W21228772015 @default.
- W2122877 crossrefType "journal-article" @default.
- W2122877 hasAuthorship W2122877A5025997398 @default.
- W2122877 hasAuthorship W2122877A5050475672 @default.
- W2122877 hasAuthorship W2122877A5057557326 @default.
- W2122877 hasAuthorship W2122877A5086051241 @default.
- W2122877 hasConcept C104317684 @default.
- W2122877 hasConcept C10879258 @default.
- W2122877 hasConcept C153911025 @default.
- W2122877 hasConcept C153957851 @default.
- W2122877 hasConcept C19014433 @default.
- W2122877 hasConcept C195500695 @default.
- W2122877 hasConcept C24586158 @default.
- W2122877 hasConcept C28859421 @default.
- W2122877 hasConcept C54355233 @default.
- W2122877 hasConcept C552990157 @default.
- W2122877 hasConcept C67705224 @default.
- W2122877 hasConcept C86803240 @default.
- W2122877 hasConcept C95444343 @default.
- W2122877 hasConceptScore W2122877C104317684 @default.
- W2122877 hasConceptScore W2122877C10879258 @default.
- W2122877 hasConceptScore W2122877C153911025 @default.
- W2122877 hasConceptScore W2122877C153957851 @default.
- W2122877 hasConceptScore W2122877C19014433 @default.
- W2122877 hasConceptScore W2122877C195500695 @default.
- W2122877 hasConceptScore W2122877C24586158 @default.
- W2122877 hasConceptScore W2122877C28859421 @default.
- W2122877 hasConceptScore W2122877C54355233 @default.
- W2122877 hasConceptScore W2122877C552990157 @default.
- W2122877 hasConceptScore W2122877C67705224 @default.
- W2122877 hasConceptScore W2122877C86803240 @default.
- W2122877 hasConceptScore W2122877C95444343 @default.
- W2122877 hasLocation W21228771 @default.
- W2122877 hasOpenAccess W2122877 @default.
- W2122877 hasPrimaryLocation W21228771 @default.
- W2122877 hasRelatedWork W1978001298 @default.
- W2122877 hasRelatedWork W1983868803 @default.
- W2122877 hasRelatedWork W1990794432 @default.
- W2122877 hasRelatedWork W2006185473 @default.
- W2122877 hasRelatedWork W2011692933 @default.
- W2122877 hasRelatedWork W2025674041 @default.
- W2122877 hasRelatedWork W2027827205 @default.
- W2122877 hasRelatedWork W2052311312 @default.
- W2122877 hasRelatedWork W2057270489 @default.
- W2122877 hasRelatedWork W2062533583 @default.
- W2122877 hasRelatedWork W2066742790 @default.
- W2122877 hasRelatedWork W2076082820 @default.
- W2122877 hasRelatedWork W2079830354 @default.
- W2122877 hasRelatedWork W2135375117 @default.
- W2122877 hasRelatedWork W2136861527 @default.
- W2122877 hasRelatedWork W2170326731 @default.
- W2122877 hasRelatedWork W2170819005 @default.
- W2122877 hasRelatedWork W2811330735 @default.
- W2122877 hasRelatedWork W2965906678 @default.
- W2122877 hasRelatedWork W977137979 @default.
- W2122877 isParatext "false" @default.
- W2122877 isRetracted "false" @default.
- W2122877 magId "2122877" @default.
- W2122877 workType "article" @default.