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- W2122991036 abstract "Trypomastigotes attached to the wall of the hypopharynx in tsetse flies infected with Trypanosoma vivax are believed to represent the true metacyclic stage of this trypanosome. Electron microscopy demonstrates that attachment is mediated by hemidesmosome-like junctions along the flagellar membrane and that none of the trypomastigotes, either attached or free in the hypopharynx lumen, possesses a surface coat comparable with that on the metacyclics of T. brucei and T. congolense and on the bloodstream stages of all salivarian trypanosomes. As the variable antigen of bloodstream and metacyclic T. brucei is located in the surface coat, the absence of the coat from metacyclic T. vivax suggests that the mechanism of antigenic variation in this species may be somewhat different from that of antigenic variation in T. brucei, and that vaccination of cattle against T. vivax may prove a simpler proposition than vaccination against T. brucei." @default.
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- W2122991036 date "1981-01-01" @default.
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- W2122991036 title "Absence of a surface coat from metacyclic Trypanosoma v/vax: possible implications for vaccination against vivax trypanosomiasis" @default.
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- W2122991036 doi "https://doi.org/10.1016/0035-9203(81)90106-1" @default.
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