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- W2122994236 abstract "The aim of the present study was to evaluate the utility of pullulan acetate microparticles (PAMs), chitosan micropaticles (CMs), and dipalmitoylphosphatidyl-serine-liposomes (PS-Lip) as oral carriers for delivery to the intestinal Peyer's patches (PPs). To monitor PP delivery after oral administration, PAMs, CMs, and PS-Lip were radiolabeled with 99mTc. Radiolabeling efficiencies of the particles were 95±2.5% (PAMs), 87±4.3% (CMs), and 77.2±5.8% (PS-Lip). In delivery studies to the PPs, the percentage of PS-Lip taken up to the PPs was 3.8 × 10−3±0.3% of the administered dose with PS-Lip group showed significantly high uptake compared to the PAM and CM groups. These results suggest that PS-Lip may be used as a potential system for developing an oral delivery carrier. Drug Dev. Res. 67:884–889, 2006. © 2007 Wiley-Liss, Inc." @default.
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- W2122994236 date "2006-12-01" @default.
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- W2122994236 title "Radioevaluation of PAMs, CMs, and PS-Lip as an oral carrier for vaccine delivery into intestinal Peyer's patches" @default.
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- W2122994236 doi "https://doi.org/10.1002/ddr.20155" @default.
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