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- W2123017706 abstract "The early effects of hypercholesterolemia on collateral arteries were studied by light and electron microscopy. It was found that the intermediate zone of the collateral vessels rapidly accumulated lipid deposits in droplet form in their walls. In control arteries no droplets resembling neutral fat were observed. The lipid depositions were most abundant in the smooth muscle cells and were usually located in areas of cytoplasm containing abundant organelles, such as mitochondria and endoplasmic retic-ulum. The changes observed showed some resemblance to atheromatous lesions. The local factor of arterial injury due to increased haemodynamic stress on the collateral vessel wall is important in this respect. It is suggested that altered permeability conditions and metabolic failure of the collateral arterial wall are possible mechanisms contributing to lipid accumulation." @default.
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- W2123017706 date "1971-01-01" @default.
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- W2123017706 title "The Reaction of Collateral Arteries to an Atherogenic Diet" @default.
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- W2123017706 doi "https://doi.org/10.3109/14017437109135547" @default.
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