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• W2123034398 abstract "THE ANTIPHOSPHOLIPID SYNDROME (APLS) is a disorder characterized by arterial and/or venous thrombosis or recurrent fetal loss accompanied by persistent APL antibodies. 1 Wilson W.A. Gharavi A.E. Koike T. et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop. Arthritis Rheum. 1999; 42: 1309-1311 Crossref PubMed Scopus (2444) Google Scholar APL antibodies are a heterogenous group of antibodies that interact with anionic phospholipid cardiolipin (diphosphatidylglycerol) and other phospholipid-binding protein cofactors, the major one being the serum protein β2-glycoprotein I (also known as apolipoprotein H). Although these patients are at an increased risk of thrombotic complications, they paradoxically have an abnormal profile of coagulation testing exhibiting prolonged activated partial thromboplastin time (aPTT)." @default.
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• W2123034398 date "2008-10-01" @default.
• W2123034398 modified "2023-10-16" @default.
• W2123034398 title "Antiphospholipid Syndrome: Intraoperative and Postoperative Anticoagulation in Cardiac Surgery" @default.
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• W2123034398 doi "https://doi.org/10.1053/j.jvca.2008.01.021" @default.
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