FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123087376> ?p ?o ?g. }

• W2123087376 endingPage "65" @default.
• W2123087376 startingPage "61" @default.
• W2123087376 abstract "Alzheimer disease (AD) is the most frequent cause of dementia in Western countries. Putative genetic risk factors for AD are polymorphisms in the apolipoprotein E (APOE) gene and in the low-density lipoprotein receptor-related protein (LRP) gene. Our objective was to investigate the role of the APOE coding region polymorphisms ε2, ε3, and ε4 and APOE promoter variants A/T at position -491 and G/T at -219, as well as LRP polymorphism C/T, as risk factors for AD in Brazilian individuals. One hundred and twenty patients with probable AD, along with 120 controls were analyzed. A significant difference between patients and controls for ε4 alleles was observed: frequency of this allele in AD was 0.31, and 0.10 in controls. Individuals with 2 ε4 alleles had a higher risk for AD than subjects with only 1 such allele; presence of 1 ε2 allele proved protective. The presence of the T allele of the -219 polymorphism was also associated with an increased risk of AD, but this polymorphism is in linkage disequilibrium with APOE ε polymorphisms. No significant differences between patients and controls were observed for -491 APOE or LRP polymorphisms. In this Brazilian population, both the ε4 allele and T -219 polymorphism were associated with an increased risk for AD." @default.
• W2123087376 created "2016-06-24" @default.
• W2123087376 creator A5020910802 @default.
• W2123087376 creator A5048092708 @default.
• W2123087376 creator A5051701249 @default.
• W2123087376 creator A5060729286 @default.
• W2123087376 creator A5062321658 @default.
• W2123087376 creator A5063134749 @default.
• W2123087376 date "2008-01-01" @default.
• W2123087376 modified "2023-10-04" @default.
• W2123087376 title "Polymorphisms of APOE and LRP Genes in Brazilian Individuals With Alzheimer Disease" @default.
• W2123087376 cites W1545109971 @default.
• W2123087376 cites W1963671893 @default.
• W2123087376 cites W1965849733 @default.
• W2123087376 cites W1966261576 @default.
• W2123087376 cites W1966927617 @default.
• W2123087376 cites W1968892572 @default.
• W2123087376 cites W1969481688 @default.
• W2123087376 cites W1973169330 @default.
• W2123087376 cites W1973902886 @default.
• W2123087376 cites W1974231601 @default.
• W2123087376 cites W1976344633 @default.
• W2123087376 cites W1985859760 @default.
• W2123087376 cites W1991306495 @default.
• W2123087376 cites W1997913988 @default.
• W2123087376 cites W2008804609 @default.
• W2123087376 cites W2018219088 @default.
• W2123087376 cites W2021181758 @default.
• W2123087376 cites W2023906989 @default.
• W2123087376 cites W2024992323 @default.
• W2123087376 cites W2030561953 @default.
• W2123087376 cites W2035883738 @default.
• W2123087376 cites W2037075645 @default.
• W2123087376 cites W2037330433 @default.
• W2123087376 cites W2039383596 @default.
• W2123087376 cites W2042098526 @default.
• W2123087376 cites W2056451248 @default.
• W2123087376 cites W2063505049 @default.
• W2123087376 cites W2066644955 @default.
• W2123087376 cites W2069323313 @default.
• W2123087376 cites W2069638209 @default.
• W2123087376 cites W2074842521 @default.
• W2123087376 cites W2075219817 @default.
• W2123087376 cites W2075618677 @default.
• W2123087376 cites W2082506839 @default.
• W2123087376 cites W2087757733 @default.
• W2123087376 cites W2090224494 @default.
• W2123087376 cites W2097553343 @default.
• W2123087376 cites W2097567647 @default.
• W2123087376 cites W2104987607 @default.
• W2123087376 cites W2110676557 @default.
• W2123087376 cites W2111774300 @default.
• W2123087376 cites W2115404424 @default.
• W2123087376 cites W2118094114 @default.
• W2123087376 cites W2118569739 @default.
• W2123087376 cites W2121728123 @default.
• W2123087376 cites W2122807253 @default.
• W2123087376 cites W2135508686 @default.
• W2123087376 cites W2146154913 @default.
• W2123087376 cites W2154034238 @default.
• W2123087376 cites W2155646555 @default.
• W2123087376 cites W2156220037 @default.
• W2123087376 cites W2159671926 @default.
• W2123087376 doi "https://doi.org/10.1097/wad.0b013e31815a9da7" @default.
• W2123087376 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18317248" @default.
• W2123087376 hasPublicationYear "2008" @default.
• W2123087376 type Work @default.
• W2123087376 sameAs 2123087376 @default.
• W2123087376 citedByCount "23" @default.
• W2123087376 countsByYear W21230873762012 @default.
• W2123087376 countsByYear W21230873762013 @default.
• W2123087376 countsByYear W21230873762014 @default.
• W2123087376 countsByYear W21230873762015 @default.
• W2123087376 countsByYear W21230873762016 @default.
• W2123087376 countsByYear W21230873762017 @default.
• W2123087376 countsByYear W21230873762019 @default.
• W2123087376 countsByYear W21230873762021 @default.
• W2123087376 crossrefType "journal-article" @default.
• W2123087376 hasAuthorship W2123087376A5020910802 @default.
• W2123087376 hasAuthorship W2123087376A5048092708 @default.
• W2123087376 hasAuthorship W2123087376A5051701249 @default.
• W2123087376 hasAuthorship W2123087376A5060729286 @default.
• W2123087376 hasAuthorship W2123087376A5062321658 @default.
• W2123087376 hasAuthorship W2123087376A5063134749 @default.
• W2123087376 hasConcept C104317684 @default.
• W2123087376 hasConcept C126322002 @default.
• W2123087376 hasConcept C180754005 @default.
• W2123087376 hasConcept C197754878 @default.
• W2123087376 hasConcept C2779134260 @default.
• W2123087376 hasConcept C35605836 @default.
• W2123087376 hasConcept C37463918 @default.
• W2123087376 hasConcept C502032728 @default.
• W2123087376 hasConcept C54355233 @default.
• W2123087376 hasConcept C57089818 @default.
• W2123087376 hasConcept C71924100 @default.
• W2123087376 hasConcept C86803240 @default.
• W2123087376 hasConceptScore W2123087376C104317684 @default.
• W2123087376 hasConceptScore W2123087376C126322002 @default.

• next