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• W2123115302 abstract "Objectives Low‐grade elevation of C‐reactive protein (CRP) is a non‐specific inflammatory marker, used as a predictor for cardiovascular disease development and chronic inflammatory risks. Research investigating dietary influences on inflammation has focused primarily on the relationship between dietary characteristics, CRP elevation and BMI in the populations at greatest risk for cardiovascular disease, namely those in the overweight and obese ranges, often in clinical settings and/or among those middle aged or older, leaving little information about normal to underweight populations of reproductive age in ecological settings. This study evaluates impacts of dietary nutrients on serum CRP levels in a population of predominantly underweight to normal weight adult women experiencing the additional nutritional demands of lactation. Methods Data from non‐overweight breastfeeding Ariaal women of Kenya collected in 2006 were used ( n = 194). Logistic regression models were applied using low‐grade CRP elevation (hsCRP > 3 mg/L) as the outcome variable and dietary nutrients, age, BMI, and serum retinol as predictors. Results Models showed that energy intake (Kcal) and age were positive predictors of CRP elevation while folate intake, total vitamin A intake, and serum retinol concentration were protective against CRP elevation. Unlike previous studies among higher BMI populations, this study found no significant effect of dietary lipids/fatty acids or BMI on CRP elevation. Conclusions The effects of specific dietary nutrients on inflammatory status may vary with BMI or, in women, reproductive status. Further research should investigate the role of dietary fats, fatty acids, and antioxidant vitamins across populations with a wide range of BMI, including postpartum women. Am. J. Hum. Biol. 26:796–802, 2014. © 2014 Wiley Periodicals, Inc." @default.
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• W2123115302 date "2014-08-07" @default.
• W2123115302 modified "2023-10-16" @default.
• W2123115302 title "Nutrient intakes associated with elevated serum C-reactive protein concentrations in normal to underweight breastfeeding women in Northern Kenya" @default.
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• W2123115302 doi "https://doi.org/10.1002/ajhb.22600" @default.
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