FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123138919> ?p ?o ?g. }

• W2123138919 endingPage "1811" @default.
• W2123138919 startingPage "1805" @default.
• W2123138919 abstract "Andersen-Tawil syndrome (ATS) is an uncommon form of channelopathy linked to mutations in the KCNJ2 gene. Currently, little is known about the long-term arrhythmic prognosis of this disease.We conducted a retrospective multicentre study in nine French hospitals. Patients were recruited only if they were KCNJ2 mutation carriers. Thirty-six patients (female n = 22, 61%) from 20 unrelated kindred were included with a mean follow-up of 9.5 ± 8.2 years. We found 12 distinct KCNJ2 mutations in the 20 probands. Three of them were novel. Thirteen patients (36%) experienced syncope and one patient was resuscitated from cardiac arrest before diagnosis. The mean QTc interval was 439 ± 57 ms and QUc was 642 ± 64 ms. All patients had normal ejection fraction. Holter recordings in 33 patients found 11 272 premature ventricular complexes (PVCs) per day on average, 25 patients had episodes of bigeminy, and 25 patients had polymorphic PVCs. Twenty-three patients (70%) had non-sustained polymorphic ventricular tachycardia (VT), and six sustained polymorphic VT. Only one patient presented with torsades de pointes. Patients were treated with beta-blocker (n = 20), beta-blocker and amiodarone (n = 2), beta-blocker and flecainide (n = 6), or acetazolamide (n = 6). Radiofrequency ablation was attempted in five patients without clinical success. An implantable cardiac defibrillator was implanted in three patients. During follow-up, none of the patients died, four patients experienced syncope under treatment, and one patient had non-fatal cardiac arrest.Despite a severe clinical presentation with a very high rate of ventricular arrhythmias, the arrhythmic prognosis of the ATS patients is relatively good under treatment." @default.
• W2123138919 created "2016-06-24" @default.
• W2123138919 creator A5001969191 @default.
• W2123138919 creator A5008670843 @default.
• W2123138919 creator A5019626709 @default.
• W2123138919 creator A5020718588 @default.
• W2123138919 creator A5033510265 @default.
• W2123138919 creator A5034392769 @default.
• W2123138919 creator A5035850931 @default.
• W2123138919 creator A5051740188 @default.
• W2123138919 creator A5063719536 @default.
• W2123138919 creator A5073148081 @default.
• W2123138919 creator A5073397412 @default.
• W2123138919 creator A5079334226 @default.
• W2123138919 creator A5080007807 @default.
• W2123138919 creator A5086740139 @default.
• W2123138919 creator A5088156463 @default.
• W2123138919 creator A5089675674 @default.
• W2123138919 creator A5091317886 @default.
• W2123138919 date "2013-07-17" @default.
• W2123138919 modified "2023-10-17" @default.
• W2123138919 title "Cardiac characteristics and long-term outcome in Andersen-Tawil syndrome patients related to KCNJ2 mutation" @default.
• W2123138919 cites W1512781775 @default.
• W2123138919 cites W1967937532 @default.
• W2123138919 cites W1988997625 @default.
• W2123138919 cites W2016762400 @default.
• W2123138919 cites W2023128261 @default.
• W2123138919 cites W2023918009 @default.
• W2123138919 cites W2055038470 @default.
• W2123138919 cites W2063406006 @default.
• W2123138919 cites W2069699972 @default.
• W2123138919 cites W2078217942 @default.
• W2123138919 cites W2088024909 @default.
• W2123138919 cites W2092049303 @default.
• W2123138919 cites W2114758158 @default.
• W2123138919 cites W2116079650 @default.
• W2123138919 cites W2132723846 @default.
• W2123138919 cites W2136290854 @default.
• W2123138919 cites W2145253150 @default.
• W2123138919 cites W2157033897 @default.
• W2123138919 cites W2157788198 @default.
• W2123138919 cites W2161227647 @default.
• W2123138919 cites W2162311900 @default.
• W2123138919 cites W4251204652 @default.
• W2123138919 doi "https://doi.org/10.1093/europace/eut160" @default.
• W2123138919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23867365" @default.
• W2123138919 hasPublicationYear "2013" @default.
• W2123138919 type Work @default.
• W2123138919 sameAs 2123138919 @default.
• W2123138919 citedByCount "62" @default.
• W2123138919 countsByYear W21231389192013 @default.
• W2123138919 countsByYear W21231389192014 @default.
• W2123138919 countsByYear W21231389192015 @default.
• W2123138919 countsByYear W21231389192016 @default.
• W2123138919 countsByYear W21231389192017 @default.
• W2123138919 countsByYear W21231389192018 @default.
• W2123138919 countsByYear W21231389192019 @default.
• W2123138919 countsByYear W21231389192020 @default.
• W2123138919 countsByYear W21231389192021 @default.
• W2123138919 countsByYear W21231389192022 @default.
• W2123138919 countsByYear W21231389192023 @default.
• W2123138919 crossrefType "journal-article" @default.
• W2123138919 hasAuthorship W2123138919A5001969191 @default.
• W2123138919 hasAuthorship W2123138919A5008670843 @default.
• W2123138919 hasAuthorship W2123138919A5019626709 @default.
• W2123138919 hasAuthorship W2123138919A5020718588 @default.
• W2123138919 hasAuthorship W2123138919A5033510265 @default.
• W2123138919 hasAuthorship W2123138919A5034392769 @default.
• W2123138919 hasAuthorship W2123138919A5035850931 @default.
• W2123138919 hasAuthorship W2123138919A5051740188 @default.
• W2123138919 hasAuthorship W2123138919A5063719536 @default.
• W2123138919 hasAuthorship W2123138919A5073148081 @default.
• W2123138919 hasAuthorship W2123138919A5073397412 @default.
• W2123138919 hasAuthorship W2123138919A5079334226 @default.
• W2123138919 hasAuthorship W2123138919A5080007807 @default.
• W2123138919 hasAuthorship W2123138919A5086740139 @default.
• W2123138919 hasAuthorship W2123138919A5088156463 @default.
• W2123138919 hasAuthorship W2123138919A5089675674 @default.
• W2123138919 hasAuthorship W2123138919A5091317886 @default.
• W2123138919 hasBestOaLocation W21231389191 @default.
• W2123138919 hasConcept C113217602 @default.
• W2123138919 hasConcept C118441451 @default.
• W2123138919 hasConcept C126322002 @default.
• W2123138919 hasConcept C164705383 @default.
• W2123138919 hasConcept C190712762 @default.
• W2123138919 hasConcept C2776331378 @default.
• W2123138919 hasConcept C2778094803 @default.
• W2123138919 hasConcept C2778178275 @default.
• W2123138919 hasConcept C2778198053 @default.
• W2123138919 hasConcept C2779161974 @default.
• W2123138919 hasConcept C2779837460 @default.
• W2123138919 hasConcept C2780486423 @default.
• W2123138919 hasConcept C42219234 @default.
• W2123138919 hasConcept C519063684 @default.
• W2123138919 hasConcept C71924100 @default.
• W2123138919 hasConcept C78085059 @default.
• W2123138919 hasConceptScore W2123138919C113217602 @default.
• W2123138919 hasConceptScore W2123138919C118441451 @default.

• next