Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123146494> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2123146494 abstract "The present study reports alterations in lysosomal enzymes in the rat myocardium and in the effuent perfusate, following immunization with homologous heart homogenates and Freund's adjuvant, and records the effect of isoproterenol on enzyme release, employing isolated perfused rat hearts. Pathological findings in the myocardium were found in the isoproterenol treated animals with or without prior immunization. A selective enzyme release was observed in all groups of animals. Immunization alone decreased the activity of cathepsin D in the myocardium but increased its activity in the effluent perfusate. Although myocardial acid phosphatase activity was increased in all experimental animals, this enzyme was not released into the effluent perfusate. It is suggested that the cause of the increased enzyme release after immunization may be due to alterations in membrane permeability. Isoproterenol alone increased the activity of cathepsin D and β-glucuronidase in the myocardial tissue, but only cathepsin D was found in the effluent perfusate. Some of the findings present in the above groups of animals were also encountered in animals treated with isoproterenol after immunization. No correlation was found between the increased enzyme activity encountered in the effluent perfusate and the extent of myocardial damage." @default.
- W2123146494 created "2016-06-24" @default.
- W2123146494 creator A5054812618 @default.
- W2123146494 creator A5079930010 @default.
- W2123146494 date "1977-11-01" @default.
- W2123146494 modified "2023-09-24" @default.
- W2123146494 title "Lysosomal enzyme release in the isolated perfused heart of immunized rats" @default.
- W2123146494 cites W1662352477 @default.
- W2123146494 cites W1775749144 @default.
- W2123146494 cites W1984189188 @default.
- W2123146494 cites W2005670096 @default.
- W2123146494 cites W2006191733 @default.
- W2123146494 cites W2016123960 @default.
- W2123146494 cites W2023440356 @default.
- W2123146494 cites W2023778659 @default.
- W2123146494 cites W2027625639 @default.
- W2123146494 cites W2042577218 @default.
- W2123146494 cites W2055573006 @default.
- W2123146494 cites W2060016734 @default.
- W2123146494 cites W2063475805 @default.
- W2123146494 cites W2068550594 @default.
- W2123146494 cites W2077071285 @default.
- W2123146494 cites W2080711236 @default.
- W2123146494 cites W2088878826 @default.
- W2123146494 cites W2099100804 @default.
- W2123146494 cites W2102126892 @default.
- W2123146494 cites W2104553506 @default.
- W2123146494 cites W2139356293 @default.
- W2123146494 cites W2152387828 @default.
- W2123146494 cites W2166848733 @default.
- W2123146494 cites W2223155177 @default.
- W2123146494 cites W2407781290 @default.
- W2123146494 cites W2409272520 @default.
- W2123146494 cites W2411785424 @default.
- W2123146494 cites W2415561049 @default.
- W2123146494 doi "https://doi.org/10.1016/s0022-2828(77)80013-8" @default.
- W2123146494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/412979" @default.
- W2123146494 hasPublicationYear "1977" @default.
- W2123146494 type Work @default.
- W2123146494 sameAs 2123146494 @default.
- W2123146494 citedByCount "2" @default.
- W2123146494 crossrefType "journal-article" @default.
- W2123146494 hasAuthorship W2123146494A5054812618 @default.
- W2123146494 hasAuthorship W2123146494A5079930010 @default.
- W2123146494 hasConcept C126322002 @default.
- W2123146494 hasConcept C134018914 @default.
- W2123146494 hasConcept C159654299 @default.
- W2123146494 hasConcept C173633252 @default.
- W2123146494 hasConcept C181199279 @default.
- W2123146494 hasConcept C185592680 @default.
- W2123146494 hasConcept C203014093 @default.
- W2123146494 hasConcept C21547065 @default.
- W2123146494 hasConcept C2780801004 @default.
- W2123146494 hasConcept C28212737 @default.
- W2123146494 hasConcept C55493867 @default.
- W2123146494 hasConcept C71924100 @default.
- W2123146494 hasConcept C86803240 @default.
- W2123146494 hasConcept C98274493 @default.
- W2123146494 hasConceptScore W2123146494C126322002 @default.
- W2123146494 hasConceptScore W2123146494C134018914 @default.
- W2123146494 hasConceptScore W2123146494C159654299 @default.
- W2123146494 hasConceptScore W2123146494C173633252 @default.
- W2123146494 hasConceptScore W2123146494C181199279 @default.
- W2123146494 hasConceptScore W2123146494C185592680 @default.
- W2123146494 hasConceptScore W2123146494C203014093 @default.
- W2123146494 hasConceptScore W2123146494C21547065 @default.
- W2123146494 hasConceptScore W2123146494C2780801004 @default.
- W2123146494 hasConceptScore W2123146494C28212737 @default.
- W2123146494 hasConceptScore W2123146494C55493867 @default.
- W2123146494 hasConceptScore W2123146494C71924100 @default.
- W2123146494 hasConceptScore W2123146494C86803240 @default.
- W2123146494 hasConceptScore W2123146494C98274493 @default.
- W2123146494 hasLocation W21231464941 @default.
- W2123146494 hasLocation W21231464942 @default.
- W2123146494 hasOpenAccess W2123146494 @default.
- W2123146494 hasPrimaryLocation W21231464941 @default.
- W2123146494 hasRelatedWork W1966504330 @default.
- W2123146494 hasRelatedWork W1979139803 @default.
- W2123146494 hasRelatedWork W2030889776 @default.
- W2123146494 hasRelatedWork W2037631372 @default.
- W2123146494 hasRelatedWork W2040058909 @default.
- W2123146494 hasRelatedWork W2064362993 @default.
- W2123146494 hasRelatedWork W2090960426 @default.
- W2123146494 hasRelatedWork W2132898409 @default.
- W2123146494 hasRelatedWork W2391409986 @default.
- W2123146494 hasRelatedWork W2899084033 @default.
- W2123146494 isParatext "false" @default.
- W2123146494 isRetracted "false" @default.
- W2123146494 magId "2123146494" @default.
- W2123146494 workType "article" @default.