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• W2123179912 abstract "CpG methylation of the human papillomavirus upstream regulatory region has previously been shown to reduce virus promoter activity. Here, we demonstrate that methylation of the CpG dinucleotides contained within the binding site of the human papillomavirus type 16 E2 protein has a direct effect on the interaction of this protein with DNA. Methylation of both CpG dinucleotides within the E2 site abolishes the binding of E2." @default.
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• W2123179912 date "1996-10-01" @default.
• W2123179912 modified "2023-10-06" @default.
• W2123179912 title "CpG methylation directly inhibits binding of the human papillomavirus type 16 E2 protein to specific DNA sequences" @default.
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• W2123179912 doi "https://doi.org/10.1128/jvi.70.10.7233-7235.1996" @default.
• W2123179912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/190779" @default.
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