Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123201857> ?p ?o ?g. }
- W2123201857 endingPage "952" @default.
- W2123201857 startingPage "943" @default.
- W2123201857 abstract "In Europe, short-term radiotherapy is increasingly used in the primary management of rectal cancer. In the United States, postoperative chemoradiotherapy is the standard treatment of choice. The rationale and indications for radiotherapy and possible combinations with chemotherapy are discussed and an overview of all of the randomised trials containing radiotherapy as one randomisation arm is given. Three major indications for radiotherapy can be identified: the reduction of local recurrences in mobile rectal cancer, downstaging of the tumour in primary irresectable tumours and downsizing of low-lying tumours in attempts to more frequently perform a sphincter-saving procedure. For reduction of local recurrences, radiotherapy can be given either pre- or postoperatively, although preoperative therapy is more dose-efficient. Short-term preoperative radiotherapy reduces the number of recurrences and improves survival. Improved survival is also reported after postoperative radiotherapy in combination with chemotherapy, however, the relevance of the radiotherapy component is discussed. Although the debate about radiotherapy is still ongoing, we strongly believe that the results demonstrate that short-term preoperative radiotherapy is the treatment of choice for resectable rectal cancer." @default.
- W2123201857 created "2016-06-24" @default.
- W2123201857 creator A5011488517 @default.
- W2123201857 creator A5057158252 @default.
- W2123201857 date "2002-05-01" @default.
- W2123201857 modified "2023-09-27" @default.
- W2123201857 title "The role of radiotherapy in rectal cancer" @default.
- W2123201857 cites W129347924 @default.
- W2123201857 cites W1492190372 @default.
- W2123201857 cites W1558442961 @default.
- W2123201857 cites W1585172067 @default.
- W2123201857 cites W1884971637 @default.
- W2123201857 cites W1896630734 @default.
- W2123201857 cites W1899767765 @default.
- W2123201857 cites W1957155552 @default.
- W2123201857 cites W1963782590 @default.
- W2123201857 cites W1967853538 @default.
- W2123201857 cites W1968698109 @default.
- W2123201857 cites W1969227627 @default.
- W2123201857 cites W1969561516 @default.
- W2123201857 cites W1974902120 @default.
- W2123201857 cites W1978224105 @default.
- W2123201857 cites W1978381377 @default.
- W2123201857 cites W1985403999 @default.
- W2123201857 cites W19910853 @default.
- W2123201857 cites W1992798305 @default.
- W2123201857 cites W1994513558 @default.
- W2123201857 cites W1997097621 @default.
- W2123201857 cites W2002431717 @default.
- W2123201857 cites W2008833109 @default.
- W2123201857 cites W2009016003 @default.
- W2123201857 cites W2012058107 @default.
- W2123201857 cites W2015288699 @default.
- W2123201857 cites W2018568783 @default.
- W2123201857 cites W2020223712 @default.
- W2123201857 cites W2020956130 @default.
- W2123201857 cites W2021416608 @default.
- W2123201857 cites W2023557462 @default.
- W2123201857 cites W2024289087 @default.
- W2123201857 cites W2027469879 @default.
- W2123201857 cites W2040927823 @default.
- W2123201857 cites W2044138832 @default.
- W2123201857 cites W2050020104 @default.
- W2123201857 cites W2057579848 @default.
- W2123201857 cites W2057975405 @default.
- W2123201857 cites W2059491071 @default.
- W2123201857 cites W2067398055 @default.
- W2123201857 cites W2069793735 @default.
- W2123201857 cites W2072840628 @default.
- W2123201857 cites W2074716610 @default.
- W2123201857 cites W2076134983 @default.
- W2123201857 cites W2077165146 @default.
- W2123201857 cites W2083062294 @default.
- W2123201857 cites W2083716454 @default.
- W2123201857 cites W2084656737 @default.
- W2123201857 cites W2089714928 @default.
- W2123201857 cites W2093522162 @default.
- W2123201857 cites W2096942520 @default.
- W2123201857 cites W2102966659 @default.
- W2123201857 cites W2105150213 @default.
- W2123201857 cites W2105768073 @default.
- W2123201857 cites W2112691152 @default.
- W2123201857 cites W2124365856 @default.
- W2123201857 cites W2128069972 @default.
- W2123201857 cites W2131629863 @default.
- W2123201857 cites W2132565869 @default.
- W2123201857 cites W2135398482 @default.
- W2123201857 cites W2167555623 @default.
- W2123201857 cites W2323577539 @default.
- W2123201857 cites W2792447334 @default.
- W2123201857 cites W4233272864 @default.
- W2123201857 cites W4249829353 @default.
- W2123201857 cites W4250463418 @default.
- W2123201857 cites W4252808948 @default.
- W2123201857 cites W4294814934 @default.
- W2123201857 cites W4299366427 @default.
- W2123201857 doi "https://doi.org/10.1016/s0959-8049(02)00047-3" @default.
- W2123201857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11978519" @default.
- W2123201857 hasPublicationYear "2002" @default.
- W2123201857 type Work @default.
- W2123201857 sameAs 2123201857 @default.
- W2123201857 citedByCount "48" @default.
- W2123201857 countsByYear W21232018572012 @default.
- W2123201857 countsByYear W21232018572013 @default.
- W2123201857 countsByYear W21232018572015 @default.
- W2123201857 countsByYear W21232018572016 @default.
- W2123201857 countsByYear W21232018572017 @default.
- W2123201857 countsByYear W21232018572018 @default.
- W2123201857 countsByYear W21232018572020 @default.
- W2123201857 countsByYear W21232018572022 @default.
- W2123201857 crossrefType "journal-article" @default.
- W2123201857 hasAuthorship W2123201857A5011488517 @default.
- W2123201857 hasAuthorship W2123201857A5057158252 @default.
- W2123201857 hasConcept C121608353 @default.
- W2123201857 hasConcept C126322002 @default.
- W2123201857 hasConcept C141071460 @default.
- W2123201857 hasConcept C168563851 @default.
- W2123201857 hasConcept C2776694085 @default.