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• W2123221106 abstract "ABSTRACT The serum levels of Th2 markers, including CCL17 (thymus and activation-regulated chemokine [TARC]), CCL22 (macrophage-derived chemokine [MDC]), and soluble CD30, were measured in 101 HIV-negative tuberculosis patients, 103 healthy community controls, and 18 tuberculosis patients in recovery. The levels of CCL17/TARC (249.8 ± 19.91 versus 143.9 ± 10.54, P < 0.0001) and sCD30 (7.78 ± 0.44 versus 4.93 ± 0.23, P < 0.0001) were significantly higher in patients with active tuberculosis than in controls; however, the CCL22/MDC serum level had no statistical difference between the groups (579.9 ± 16.42 versus 556.5 ± 15.29, P = 0.298). The counts of platelet and eosinophil in the peripheral blood of patients with active tuberculosis are significantly increased as well (289.4 ± 8.14 versus 248.3 ± 5.34 [ P < 0.0001] and 165.1 ± 14.33 versus 102.5 ± 10.72 [ P = 0.0005], respectively), and the platelet counts were positively correlated with serum TARC levels (Pearson r = 0.456, P < 0.0001), which indicates a new source of Th2 bias showing in active TB patients." @default.
• W2123221106 created "2016-06-24" @default.
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• W2123221106 date "2011-01-26" @default.
• W2123221106 modified "2023-10-02" @default.
• W2123221106 title "Elevated Serum Levels of CCL17 Correlate with Increased Peripheral Blood Platelet Count in Patients with Active Tuberculosis in China" @default.
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• W2123221106 doi "https://doi.org/10.1128/cvi.00493-10" @default.
• W2123221106 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3122576" @default.
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