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- W2123312912 abstract "[(7-Chloroquinolin-4-yl)amino]chalcone derivatives derived from the corresponding 3- or 4-[(7-chloroquinolin-4-yl)amino]acetophenone were synthesized and evaluated for in vitro antimalarial and anticancer activity. The most active compounds 12, 13, 15, 17 and 19 from the 3-substituted series displayed inhibitory values against heme cristallization in the range of 93.14 ± 1.74 – 94.93 ± 1.50 % as an antimalarial mechanism and cytotoxic effect with IC50 values of 7.93 ± 2.05, 7.11 ± 2.06 and 6.95 ± 1.62 μg/mL for 13, 17 and 19 respectively against humane prostate LNCaP tumor cells." @default.
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- W2123312912 date "2009-01-01" @default.
- W2123312912 modified "2023-09-30" @default.
- W2123312912 title "Synthesis of 7-chloroquinolinyl-4-" @default.
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- W2123312912 doi "https://doi.org/10.3797/scipharm.0905-07" @default.
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