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• W2123397286 abstract "RATIONALE: Describe demographic and clinical presentation, of children diagnosed with Eosinophilic Esophagitis (EE), report atopic characteristics and sensitization profile to food and environmental allergens.METHOD: Cross sectional study with 24 patients from 1 month to 18 years with gastrointestinal symptoms and EE confirmed by histopathology of esophageal biopsies.Evaluation of age, sex, symptoms, and atopy with patient history of allergies, skin prick test and immunoassays test for food and environmental allergens.RESULTS: 54.2% were female and 45.8% were male, median age was 7 years old. The largest group age was 5 to 10 years old (46%), most common presenting symptoms were epigastric pain,42%, abdominal pain, 33% and GER with 21%. In the group age of 0 to 4 years old, the most common presenting symptom was vomiting. 83% presented sensitization to at least one allergen. 35% of the allergies were to environmental allergens, most common dust mite. Food allergies were present in 15% of the patients; allergies to egg, wheat and soybean (12% each one) were the most prevalent.CONCLUSIONS: This is the first study describing children with EE in Puerto Rico. Slight female to male predominance. Group age frequency) was compatible with reported literature. Most common presenting symptom was epigastric pain and vomiting. Although food allergens are the proposed offending agents involved in the pathogenesis of EE, only 20% of the pediatric patients with EE in our study presented any food allergy. Environmental allergies were most prevalent. 17% of our patients were not allergic to the used allergy testing. RATIONALE: Describe demographic and clinical presentation, of children diagnosed with Eosinophilic Esophagitis (EE), report atopic characteristics and sensitization profile to food and environmental allergens. METHOD: Cross sectional study with 24 patients from 1 month to 18 years with gastrointestinal symptoms and EE confirmed by histopathology of esophageal biopsies. Evaluation of age, sex, symptoms, and atopy with patient history of allergies, skin prick test and immunoassays test for food and environmental allergens. RESULTS: 54.2% were female and 45.8% were male, median age was 7 years old. The largest group age was 5 to 10 years old (46%), most common presenting symptoms were epigastric pain,42%, abdominal pain, 33% and GER with 21%. In the group age of 0 to 4 years old, the most common presenting symptom was vomiting. 83% presented sensitization to at least one allergen. 35% of the allergies were to environmental allergens, most common dust mite. Food allergies were present in 15% of the patients; allergies to egg, wheat and soybean (12% each one) were the most prevalent. CONCLUSIONS: This is the first study describing children with EE in Puerto Rico. Slight female to male predominance. Group age frequency) was compatible with reported literature. Most common presenting symptom was epigastric pain and vomiting. Although food allergens are the proposed offending agents involved in the pathogenesis of EE, only 20% of the pediatric patients with EE in our study presented any food allergy. Environmental allergies were most prevalent. 17% of our patients were not allergic to the used allergy testing." @default.
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• W2123397286 date "2009-02-01" @default.
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• W2123397286 title "Food and environmental allergies in children with Eosinophilic Esophagitis" @default.
• W2123397286 doi "https://doi.org/10.1016/j.jaci.2008.12.950" @default.
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