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- W2123404507 abstract "Introduction: Cyclophosphamide (CYP) is an alkylating agent, which is used in different diseases. It has several important side effects on ovaries. Tribulus terrestris extract (TTE) has different steroidal saponins and has been used for a long time as an aphrodisiac. The aim of this study was to evaluate the protective effects of TTE on the toxicity of CYP in the ovary of rats. Methods: Forty-eight female rats were divided into 6 groups. First group received only normal saline. Group 2, 3 and 5 received CYP (30 mg/kg, 2 times/week for 7 weeks). Groups 3 and 4 received TTE (10 mg/kg, 2 times/week for 10 weeks) and groups 5 and 6 received vitamin C (80 mg/kg, 2 times/week for 7 weeks). At the end of study, blood was collected and the rats were sacrificed. Ovaries were dissected for the histopathological study. Serum levels of estrogen" @default.
- W2123404507 created "2016-06-24" @default.
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- W2123404507 date "2013-07-10" @default.
- W2123404507 modified "2023-09-23" @default.
- W2123404507 title "Effects of Tribulus Terrestris extract and Vitamin C on changes induced by cyclophosphamide in the rat ovary" @default.
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