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- W2123410822 abstract "Assessment of bone disproportion is one of the routine radiological procedures frequently performed at a skeletal dysplasia diagnosis center. The existing knowledge on skeletal dysplasia patterns is more qualitative than quantitative, and the commonly applied diagnostic procedure is the manual, atlas-based evaluation of radiographs (including the hand) by an expert. A computer-aided diagnosis package (CAD) for bone age assessment was improved to analyze hand radiographs of skeletal dysplasia subjects with manifested hand bone abnormalities. The CAD software can automatically measure the lengths of phalangeal bones, compare them with those obtained from normal subjects collected in the Digital Hand Atlas (DHA), and recognize selected abnormality patterns. We have tested our method based on brachydactyly type A cases from the skeletal dysplasia diagnosis center that were matched with subjects from DHA in the age range of 2-12 years. New quantitative results obtained from this study have the potential to enrich the qualitative criteria currently utilized in the manual evaluation of abnormal bones, and thereby improve the performance of the diagnostic procedure." @default.
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- W2123410822 date "2010-01-01" @default.
- W2123410822 modified "2023-09-26" @default.
- W2123410822 title "Computerized Evaluation of Abnormal Hand Bone Patterns in Skeletal Dysplasias" @default.
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- W2123410822 doi "https://doi.org/10.1007/978-3-642-13105-9_13" @default.
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