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- W2123447687 abstract "textabstractAsthma was first described in the medical literature of Greek antiquity. It is difficultto determine whether by referring to “asthma”, Hippocrates and his school (460-360B.C.) meant an autonomous clinical entity or a symptom. The clinical presentation ofasthma nowadays has probably changed little compared to 200 years ago. However,there are now many more people with asthma. According to the Global Initiative forAsthma: ‘Asthma is a disorder defined by its clinical, physiological, and pathologicalcharacteristics. The predominant feature of the clinical history is episodic shortness ofbreath, particularly at night, often accompanied by cough. Wheezing appreciated onauscultation of the chest is the most common physical finding. The main physiologicalfeature of asthma is episodic airway obstruction characterized by expiratory airflowlimitation. The dominant pathological feature is airway inflammation, sometimesassociated with airway structural changes (www.ginasthma.org).’ In Western countriesthe prevalence of childhood asthma and atopic diseases has increased dramaticallyduring the end of the last century. There are large differences in asthma prevalencebetween Western countries, and between the different continents. In Westerncountries, asthma is one of the most frequent chronic disorders in childhood, with ahigh burden of morbidity, absenteeism from school, health care costs and reducedquality of life." @default.
- W2123447687 created "2016-06-24" @default.
- W2123447687 creator A5031515706 @default.
- W2123447687 date "2013-04-12" @default.
- W2123447687 modified "2023-09-24" @default.
- W2123447687 title "Exhaled nitric oxide and asthma in childhood" @default.
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