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- W2123453432 abstract "We aimed to investigate the effect of cell-cell dipole interactions in the equilibrium distributions in dielectrophoretic devices.We used a three dimensional coupled Monte Carlo-Poisson method to theoretically study the final distribution of a system of uncharged polarizable particles suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. The simulated distributions have been compared with experimental ones observed in the case of MDA-MB-231 cells in the same operating conditions.The real and simulated distributions are consistent. In both cases the cells distribution near the electrodes is dominated by cell-cell dipole interactions which generate long chains.The agreement between real and simulated cells' distributions demonstrate the method's reliability. The distribution are dominated by cell-cell dipole interactions even at low density regimes (105 cell/ml). An improved estimate for the density threshold governing the interaction free regime is suggested." @default.
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- W2123453432 date "2014-01-01" @default.
- W2123453432 modified "2023-10-13" @default.
- W2123453432 title "Theoretical and experimental study of the role of cell-cell dipole interaction in dielectrophoretic devices: application to polynomial electrodes" @default.
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- W2123453432 doi "https://doi.org/10.1186/1475-925x-13-71" @default.
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