Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123454417> ?p ?o ?g. }
- W2123454417 endingPage "716" @default.
- W2123454417 startingPage "712" @default.
- W2123454417 abstract "intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table thickening would encroach on ICV and could mask actual brain atrophy.we investigated the effect that thickening might have on the associations between brain atrophy and cognition.the sample comprised 57 non-demented older adults who underwent structural brain MRI at mean age 72.7 ± 0.7 years and were assessed on cognitive ability at mean age 11 and 73 years. Principal component analysis was used to derive factors of general cognitive ability (g), information processing speed and memory from the recorded cognitive ability data. The total brain tissue volume and ICV with (estimated original ICV) and without (current ICV) adjusting for the effects of inner table skull thickening were measured. General linear modelling was used to test for associations.all cognitive ability variables were significantly (P < 0.01) associated with percentage total brain volume in ICV measured without adjusting for skull thickening (g: η(2) = 0.177, speed: η(2) = 0.264 and memory: η(2) = 0.132). After accounting for skull thickening, only speed was significantly associated with percentage total brain volume in ICV (η(2) = 0.085, P = 0.034), not g or memory.not accounting for skull thickening when computing ICV can distort the association between brain atrophy and cognitive ability in old age. Larger samples are required to determine the true effect." @default.
- W2123454417 created "2016-06-24" @default.
- W2123454417 creator A5003194031 @default.
- W2123454417 creator A5028857433 @default.
- W2123454417 creator A5033685419 @default.
- W2123454417 creator A5061348073 @default.
- W2123454417 creator A5074357173 @default.
- W2123454417 creator A5078185083 @default.
- W2123454417 creator A5078677480 @default.
- W2123454417 creator A5079216137 @default.
- W2123454417 creator A5080452728 @default.
- W2123454417 creator A5085081184 @default.
- W2123454417 creator A5087078152 @default.
- W2123454417 date "2014-06-16" @default.
- W2123454417 modified "2023-10-06" @default.
- W2123454417 title "Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing" @default.
- W2123454417 cites W1963657493 @default.
- W2123454417 cites W2006046557 @default.
- W2123454417 cites W2014614026 @default.
- W2123454417 cites W2021132673 @default.
- W2123454417 cites W2034510106 @default.
- W2123454417 cites W2140575485 @default.
- W2123454417 cites W2162424711 @default.
- W2123454417 doi "https://doi.org/10.1093/ageing/afu070" @default.
- W2123454417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24936580" @default.
- W2123454417 hasPublicationYear "2014" @default.
- W2123454417 type Work @default.
- W2123454417 sameAs 2123454417 @default.
- W2123454417 citedByCount "6" @default.
- W2123454417 countsByYear W21234544172017 @default.
- W2123454417 countsByYear W21234544172018 @default.
- W2123454417 countsByYear W21234544172020 @default.
- W2123454417 countsByYear W21234544172021 @default.
- W2123454417 countsByYear W21234544172022 @default.
- W2123454417 countsByYear W21234544172023 @default.
- W2123454417 crossrefType "journal-article" @default.
- W2123454417 hasAuthorship W2123454417A5003194031 @default.
- W2123454417 hasAuthorship W2123454417A5028857433 @default.
- W2123454417 hasAuthorship W2123454417A5033685419 @default.
- W2123454417 hasAuthorship W2123454417A5061348073 @default.
- W2123454417 hasAuthorship W2123454417A5074357173 @default.
- W2123454417 hasAuthorship W2123454417A5078185083 @default.
- W2123454417 hasAuthorship W2123454417A5078677480 @default.
- W2123454417 hasAuthorship W2123454417A5079216137 @default.
- W2123454417 hasAuthorship W2123454417A5080452728 @default.
- W2123454417 hasAuthorship W2123454417A5085081184 @default.
- W2123454417 hasAuthorship W2123454417A5087078152 @default.
- W2123454417 hasBestOaLocation W21234544171 @default.
- W2123454417 hasConcept C105702510 @default.
- W2123454417 hasConcept C118552586 @default.
- W2123454417 hasConcept C126322002 @default.
- W2123454417 hasConcept C126348684 @default.
- W2123454417 hasConcept C126838900 @default.
- W2123454417 hasConcept C143409427 @default.
- W2123454417 hasConcept C145940234 @default.
- W2123454417 hasConcept C15744967 @default.
- W2123454417 hasConcept C164705383 @default.
- W2123454417 hasConcept C169760540 @default.
- W2123454417 hasConcept C169900460 @default.
- W2123454417 hasConcept C185592680 @default.
- W2123454417 hasConcept C185711340 @default.
- W2123454417 hasConcept C2779300802 @default.
- W2123454417 hasConcept C2779559920 @default.
- W2123454417 hasConcept C2781172350 @default.
- W2123454417 hasConcept C548259974 @default.
- W2123454417 hasConcept C58693492 @default.
- W2123454417 hasConcept C65835030 @default.
- W2123454417 hasConcept C71924100 @default.
- W2123454417 hasConceptScore W2123454417C105702510 @default.
- W2123454417 hasConceptScore W2123454417C118552586 @default.
- W2123454417 hasConceptScore W2123454417C126322002 @default.
- W2123454417 hasConceptScore W2123454417C126348684 @default.
- W2123454417 hasConceptScore W2123454417C126838900 @default.
- W2123454417 hasConceptScore W2123454417C143409427 @default.
- W2123454417 hasConceptScore W2123454417C145940234 @default.
- W2123454417 hasConceptScore W2123454417C15744967 @default.
- W2123454417 hasConceptScore W2123454417C164705383 @default.
- W2123454417 hasConceptScore W2123454417C169760540 @default.
- W2123454417 hasConceptScore W2123454417C169900460 @default.
- W2123454417 hasConceptScore W2123454417C185592680 @default.
- W2123454417 hasConceptScore W2123454417C185711340 @default.
- W2123454417 hasConceptScore W2123454417C2779300802 @default.
- W2123454417 hasConceptScore W2123454417C2779559920 @default.
- W2123454417 hasConceptScore W2123454417C2781172350 @default.
- W2123454417 hasConceptScore W2123454417C548259974 @default.
- W2123454417 hasConceptScore W2123454417C58693492 @default.
- W2123454417 hasConceptScore W2123454417C65835030 @default.
- W2123454417 hasConceptScore W2123454417C71924100 @default.
- W2123454417 hasIssue "5" @default.
- W2123454417 hasLocation W21234544171 @default.
- W2123454417 hasLocation W21234544172 @default.
- W2123454417 hasLocation W21234544173 @default.
- W2123454417 hasOpenAccess W2123454417 @default.
- W2123454417 hasPrimaryLocation W21234544171 @default.
- W2123454417 hasRelatedWork W1977920679 @default.
- W2123454417 hasRelatedWork W1996998945 @default.
- W2123454417 hasRelatedWork W2102917482 @default.
- W2123454417 hasRelatedWork W2112736415 @default.