FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123461072> ?p ?o ?g. }

• W2123461072 endingPage "303" @default.
• W2123461072 startingPage "297" @default.
• W2123461072 abstract "Objectives In this report the associations between telomere length variation (TLV), mean telomere length in blood lymphocytes and lung cancer risk were examined. Materials and methods The study design is case–control. Cases (N = 191) were patients newly diagnosed with histologically confirmed non-small cell lung cancer. Controls (N = 207) were healthy individuals recruited from the same counties as cases and matched to cases on age and gender. Telomere fluorescent in situ hybridization was used to measure telomere features using short-term cultured blood lymphocytes. Logistic regression was used to estimate the strength of association between telomere features and lung cancer risk. Results Telomere length variation across all chromosomal ends was significantly associated with lung cancer risk; adjusted odds ratios 4.67 [95% confidence interval (CI): 1.46–14.9] and 0.46 (95% CI: 0.25–0.84) for younger (age ≤ 60) and older (age > 60) individuals, respectively. TLV and mean telomere length jointly affected lung cancer risk: when comparing individuals with short telomere length and high TLV to those with long telomere length and low TLV, adjusted odd ratios were 8.21 (95% CI: 1.71–39.5) and 0.33 (95% CI: 0.15–0.72) for younger and older individuals, respectively. Conclusions TLV in blood lymphocytes is significantly associated with lung cancer risk and the associations were modulated by age. TLV in combination with mean telomere length might be useful in identifying high risk population for lung cancer computerized tomography screening." @default.
• W2123461072 created "2016-06-24" @default.
• W2123461072 creator A5011689931 @default.
• W2123461072 creator A5013346092 @default.
• W2123461072 creator A5018863416 @default.
• W2123461072 creator A5027534599 @default.
• W2123461072 creator A5029498288 @default.
• W2123461072 creator A5048865081 @default.
• W2123461072 creator A5050126669 @default.
• W2123461072 creator A5050792044 @default.
• W2123461072 creator A5070838435 @default.
• W2123461072 creator A5079716545 @default.
• W2123461072 creator A5091893726 @default.
• W2123461072 date "2015-06-01" @default.
• W2123461072 modified "2023-09-25" @default.
• W2123461072 title "Telomere length variation: A potential new telomere biomarker for lung cancer risk" @default.
• W2123461072 cites W111108193 @default.
• W2123461072 cites W1223729236 @default.
• W2123461072 cites W1497143641 @default.
• W2123461072 cites W1600373583 @default.
• W2123461072 cites W1676646253 @default.
• W2123461072 cites W1964050666 @default.
• W2123461072 cites W1964151664 @default.
• W2123461072 cites W1965797097 @default.
• W2123461072 cites W1967575728 @default.
• W2123461072 cites W1983673827 @default.
• W2123461072 cites W1990423201 @default.
• W2123461072 cites W1995635039 @default.
• W2123461072 cites W1998590670 @default.
• W2123461072 cites W1999872096 @default.
• W2123461072 cites W2005996436 @default.
• W2123461072 cites W2013073993 @default.
• W2123461072 cites W2014013625 @default.
• W2123461072 cites W2017426888 @default.
• W2123461072 cites W2018182154 @default.
• W2123461072 cites W2018369441 @default.
• W2123461072 cites W2021489383 @default.
• W2123461072 cites W2023875413 @default.
• W2123461072 cites W2027645950 @default.
• W2123461072 cites W2030255222 @default.
• W2123461072 cites W2031230149 @default.
• W2123461072 cites W2037516621 @default.
• W2123461072 cites W2042377388 @default.
• W2123461072 cites W2043204829 @default.
• W2123461072 cites W2054461612 @default.
• W2123461072 cites W2063062036 @default.
• W2123461072 cites W2068409711 @default.
• W2123461072 cites W2086316954 @default.
• W2123461072 cites W2093427603 @default.
• W2123461072 cites W2103453025 @default.
• W2123461072 cites W2107175910 @default.
• W2123461072 cites W2109269606 @default.
• W2123461072 cites W2122740168 @default.
• W2123461072 cites W2132142135 @default.
• W2123461072 cites W2137144564 @default.
• W2123461072 cites W2140383813 @default.
• W2123461072 cites W2141444502 @default.
• W2123461072 cites W2148531499 @default.
• W2123461072 cites W2149718327 @default.
• W2123461072 cites W2158047743 @default.
• W2123461072 cites W2160185049 @default.
• W2123461072 cites W2161886708 @default.
• W2123461072 cites W2163261748 @default.
• W2123461072 cites W2175722093 @default.
• W2123461072 cites W2414820372 @default.
• W2123461072 cites W4249363328 @default.
• W2123461072 cites W4253085106 @default.
• W2123461072 doi "https://doi.org/10.1016/j.lungcan.2015.03.011" @default.
• W2123461072 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4428929" @default.
• W2123461072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25840848" @default.
• W2123461072 hasPublicationYear "2015" @default.
• W2123461072 type Work @default.
• W2123461072 sameAs 2123461072 @default.
• W2123461072 citedByCount "21" @default.
• W2123461072 countsByYear W21234610722015 @default.
• W2123461072 countsByYear W21234610722016 @default.
• W2123461072 countsByYear W21234610722017 @default.
• W2123461072 countsByYear W21234610722018 @default.
• W2123461072 countsByYear W21234610722019 @default.
• W2123461072 countsByYear W21234610722020 @default.
• W2123461072 countsByYear W21234610722022 @default.
• W2123461072 countsByYear W21234610722023 @default.
• W2123461072 crossrefType "journal-article" @default.
• W2123461072 hasAuthorship W2123461072A5011689931 @default.
• W2123461072 hasAuthorship W2123461072A5013346092 @default.
• W2123461072 hasAuthorship W2123461072A5018863416 @default.
• W2123461072 hasAuthorship W2123461072A5027534599 @default.
• W2123461072 hasAuthorship W2123461072A5029498288 @default.
• W2123461072 hasAuthorship W2123461072A5048865081 @default.
• W2123461072 hasAuthorship W2123461072A5050126669 @default.
• W2123461072 hasAuthorship W2123461072A5050792044 @default.
• W2123461072 hasAuthorship W2123461072A5070838435 @default.
• W2123461072 hasAuthorship W2123461072A5079716545 @default.
• W2123461072 hasAuthorship W2123461072A5091893726 @default.
• W2123461072 hasBestOaLocation W21234610722 @default.
• W2123461072 hasConcept C121608353 @default.
• W2123461072 hasConcept C126322002 @default.
• W2123461072 hasConcept C142724271 @default.

• next