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- W2123638354 abstract "Cyclic Neutropenia is a rare hematologic disease in which regular episodes of severe neutropenia, usually accompanied by fever, mucous membrane ulceration, and abdominal pain and tenderness, recur at approximately 3-wk intervals.1,2 A patient with this disease, who developed localized colon necrosis, peritonitis, and clostridial septicemia during a neutropenic period, was treated recently. Exteriorization of the colon prior to perforation allowed for staged elective resection subsequently and provided a unique opportunity to observe the cyclic formation of mucosal ulcerations in the large bowel. Although cyclic neutropenia is rarely accompanied by life-threatening infection, this case serves to emphasize the potential severity of such a complication. Furthermore, abdominal pain, should it occur, merits careful observation since unrecognized colon necrosis has been the cause of death in previously reported cases of this disease.4,5" @default.
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- W2123638354 date "1973-06-01" @default.
- W2123638354 modified "2023-09-26" @default.
- W2123638354 title "Colon ulceration and perforation in Cyclic Neutropenia" @default.
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- W2123638354 doi "https://doi.org/10.1016/0022-3468(73)90105-x" @default.
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