FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2123923659> ?p ?o ?g. }

• W2123923659 endingPage "351" @default.
• W2123923659 startingPage "339" @default.
• W2123923659 abstract "Flowering locus C (FLC), a floral repressor, is a critical factor for the transition from the vegetative to the reproductive phase. Here, the mechanisms regulating the activity and stability of the FLC protein were investigated. Bimolecular fluorescence complementation and in vitro pull-down analyses showed that FLC interacts with the E3 small ubiquitin-like modifier (SUMO) ligase AtSIZ1, suggesting that AtSIZ1 is an E3 SUMO ligase for FLC. In vitro sumoylation assays showed that FLC is modified by SUMO in the presence of SUMO-activating enzyme E1 and conjugating enzyme E2, but its sumoylation is inhibited by AtSIZ1. In transgenic plants, inducible AtSIZ1 overexpression led to an increase in the concentration of FLC and delayed the post-translational decay of FLC, indicating that AtSIZ1 stabilizes FLC through direct binding. Also, the flowering time in mutant FLC (K154R, a mutation of the sumoylation site)-overexpressing plants was comparable with that in the wild type, whereas flowering was considerably delayed in FLC-overexpressing plants, supporting the notion that sumoylation is an important mechanism for FLC function. The data indicate that the sumoylation of FLC is critical for its role in the control of flowering time and that AtSIZ1 positively regulates FLC-mediated floral suppression." @default.
• W2123923659 created "2016-06-24" @default.
• W2123923659 creator A5009758226 @default.
• W2123923659 creator A5026956027 @default.
• W2123923659 creator A5034894355 @default.
• W2123923659 creator A5069027144 @default.
• W2123923659 date "2013-11-11" @default.
• W2123923659 modified "2023-10-16" @default.
• W2123923659 title "FLC-mediated flowering repression is positively regulated by sumoylation" @default.
• W2123923659 cites W1979275431 @default.
• W2123923659 cites W1983870100 @default.
• W2123923659 cites W1986606670 @default.
• W2123923659 cites W1987780245 @default.
• W2123923659 cites W1989871357 @default.
• W2123923659 cites W1993020640 @default.
• W2123923659 cites W1998409099 @default.
• W2123923659 cites W2003199010 @default.
• W2123923659 cites W2014522068 @default.
• W2123923659 cites W2014533517 @default.
• W2123923659 cites W2017594489 @default.
• W2123923659 cites W2047134964 @default.
• W2123923659 cites W2047858731 @default.
• W2123923659 cites W2048909444 @default.
• W2123923659 cites W2054537815 @default.
• W2123923659 cites W2056014639 @default.
• W2123923659 cites W2058553280 @default.
• W2123923659 cites W2070163476 @default.
• W2123923659 cites W2071636376 @default.
• W2123923659 cites W2077721732 @default.
• W2123923659 cites W2079394299 @default.
• W2123923659 cites W2083507481 @default.
• W2123923659 cites W2084117490 @default.
• W2123923659 cites W2085578783 @default.
• W2123923659 cites W2094032514 @default.
• W2123923659 cites W2102779262 @default.
• W2123923659 cites W2110404186 @default.
• W2123923659 cites W2114800743 @default.
• W2123923659 cites W2116122104 @default.
• W2123923659 cites W2117743246 @default.
• W2123923659 cites W2121225479 @default.
• W2123923659 cites W2124141147 @default.
• W2123923659 cites W2133757548 @default.
• W2123923659 cites W2134512081 @default.
• W2123923659 cites W2137068170 @default.
• W2123923659 cites W2140363516 @default.
• W2123923659 cites W2146014694 @default.
• W2123923659 cites W2148282857 @default.
• W2123923659 cites W2149638052 @default.
• W2123923659 cites W2150857291 @default.
• W2123923659 cites W2153322852 @default.
• W2123923659 cites W2154837790 @default.
• W2123923659 cites W2160736226 @default.
• W2123923659 doi "https://doi.org/10.1093/jxb/ert383" @default.
• W2123923659 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3883301" @default.
• W2123923659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24218331" @default.
• W2123923659 hasPublicationYear "2013" @default.
• W2123923659 type Work @default.
• W2123923659 sameAs 2123923659 @default.
• W2123923659 citedByCount "34" @default.
• W2123923659 countsByYear W21239236592014 @default.
• W2123923659 countsByYear W21239236592015 @default.
• W2123923659 countsByYear W21239236592016 @default.
• W2123923659 countsByYear W21239236592017 @default.
• W2123923659 countsByYear W21239236592018 @default.
• W2123923659 countsByYear W21239236592019 @default.
• W2123923659 countsByYear W21239236592020 @default.
• W2123923659 countsByYear W21239236592021 @default.
• W2123923659 countsByYear W21239236592022 @default.
• W2123923659 countsByYear W21239236592023 @default.
• W2123923659 crossrefType "journal-article" @default.
• W2123923659 hasAuthorship W2123923659A5009758226 @default.
• W2123923659 hasAuthorship W2123923659A5026956027 @default.
• W2123923659 hasAuthorship W2123923659A5034894355 @default.
• W2123923659 hasAuthorship W2123923659A5069027144 @default.
• W2123923659 hasBestOaLocation W21239236591 @default.
• W2123923659 hasConcept C104317684 @default.
• W2123923659 hasConcept C123243835 @default.
• W2123923659 hasConcept C134459356 @default.
• W2123923659 hasConcept C143065580 @default.
• W2123923659 hasConcept C150194340 @default.
• W2123923659 hasConcept C153911025 @default.
• W2123923659 hasConcept C158448853 @default.
• W2123923659 hasConcept C171350616 @default.
• W2123923659 hasConcept C175114707 @default.
• W2123923659 hasConcept C181199279 @default.
• W2123923659 hasConcept C186310378 @default.
• W2123923659 hasConcept C25602115 @default.
• W2123923659 hasConcept C55493867 @default.
• W2123923659 hasConcept C86339819 @default.
• W2123923659 hasConcept C86803240 @default.
• W2123923659 hasConcept C95444343 @default.
• W2123923659 hasConceptScore W2123923659C104317684 @default.
• W2123923659 hasConceptScore W2123923659C123243835 @default.
• W2123923659 hasConceptScore W2123923659C134459356 @default.
• W2123923659 hasConceptScore W2123923659C143065580 @default.
• W2123923659 hasConceptScore W2123923659C150194340 @default.
• W2123923659 hasConceptScore W2123923659C153911025 @default.
• W2123923659 hasConceptScore W2123923659C158448853 @default.

• next