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• W2123936845 abstract "The role of transition metal ions in atherogenesis is controversial; they can participate in the hydroxyl radical generation and catalyze the reactive oxygen species neutralization reaction as cofactors of antioxidant enzymes. Using EPR spectroscopy, we revealed that 70% of the samples of aorta with atherosclerotic lesions possessed superoxide dismutase activity, 100% of the samples initiated Fenton reaction and demonstrated the presence of manganese paramagnetic centers. The sodA gene encoding manganese-dependent bacterial superoxide dismutase was not found in the samples of atherosclerotic plaques by PCR using degenerate primers. The data obtained indicates the perspectives of manganese analysis as a marker element in the express diagnostics of atherosclerosis." @default.
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• W2123936845 date "2012-01-01" @default.
• W2123936845 modified "2023-10-07" @default.
• W2123936845 title "Manganese in atherogenesis: detection, origin, and role" @default.
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• W2123936845 doi "https://doi.org/10.18097/pbmc20125803291" @default.
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