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• W2123985355 startingPage "1980" @default.
• W2123985355 abstract "Many avian species exhibit an extraordinary ability to exercise under hypoxic condition compared with mammals, and more efficient pulmonary O 2 transport has been hypothesized to contribute to this avian advantage. We studied six emus ( Dromaius novaehollandaie, 4–6 mo old, 25–40 kg) at rest and during treadmill exercise in normoxia and hypoxia (inspired O 2 fraction ≈ 0.13). The multiple inert gas elimination technique was used to measure ventilation-perfusion (V˙/Q˙) distribution of the lung and calculate cardiac output and parabronchial ventilation. In both normoxia and hypoxia, exercise increased arterial Po 2 and decreased arterial Pco 2 , reflecting hyperventilation, whereas pH remained unchanged. The V˙/Q˙ distribution was unimodal, with a log standard deviation of perfusion distribution = 0.60 ± 0.06 at rest; this did not change significantly with either exercise or hypoxia. Intrapulmonary shunt was <1% of the cardiac output in all conditions. CO 2 elimination was enhanced by hypoxia and exercise, but O 2 exchange was not affected by exercise in normoxia or hypoxia. The stability of V˙/Q˙ matching under conditions of hypoxia and exercise may be advantageous for birds flying at altitude." @default.
• W2123985355 created "2016-06-24" @default.
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• W2123985355 date "2002-12-01" @default.
• W2123985355 modified "2023-09-27" @default.
• W2123985355 title "Ventilation-perfusion inequality during normoxic and hypoxic exercise in the emu" @default.
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• W2123985355 doi "https://doi.org/10.1152/japplphysiol.01108.2001" @default.
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