FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124013616> ?p ?o ?g. }

• W2124013616 endingPage "203" @default.
• W2124013616 startingPage "192" @default.
• W2124013616 abstract "Abstract In addition to establishing symbiotic relationships with arbuscular mycorrhizal fungi, legumes also enter into a nitrogen-fixing symbiosis with rhizobial bacteria that results in the formation of root nodules. Several genes involved in the development of both arbuscular mycorrhiza and legume nodulation have been cloned in model legumes. Among them, Medicago truncatula DMI1 (DOESN'T MAKE INFECTIONS1) is required for the generation of nucleus-associated calcium spikes in response to the rhizobial signaling molecule Nod factor. DMI1 encodes a membrane protein with striking similarities to the Methanobacterium thermoautotrophicum potassium channel (MthK). The cytosolic C terminus of DMI1 contains a RCK (regulator of the conductance of K+) domain that in MthK acts as a calcium-regulated gating ring controlling the activity of the channel. Here we show that a dmi1 mutant lacking the entire C terminus acts as a dominant-negative allele interfering with the formation of nitrogen-fixing nodules and abolishing the induction of calcium spikes by the G-protein agonist Mastoparan. Using both the full-length DMI1 and this dominant-negative mutant protein we show that DMI1 increases the sensitivity of a sodium- and lithium-hypersensitive yeast (Saccharomyces cerevisiae) mutant toward those ions and that the C-terminal domain plays a central role in regulating this response. We also show that DMI1 greatly reduces the release of calcium from internal stores in yeast, while the dominant-negative allele appears to have the opposite effect. This work suggests that DMI1 is not directly responsible for Nod factor-induced calcium changes, but does have the capacity to regulate calcium channels in both yeast and plants." @default.
• W2124013616 created "2016-06-24" @default.
• W2124013616 creator A5012848667 @default.
• W2124013616 creator A5015269349 @default.
• W2124013616 creator A5018458414 @default.
• W2124013616 creator A5021534135 @default.
• W2124013616 creator A5027370983 @default.
• W2124013616 creator A5035630533 @default.
• W2124013616 creator A5042482500 @default.
• W2124013616 creator A5054322455 @default.
• W2124013616 creator A5060722976 @default.
• W2124013616 creator A5060893632 @default.
• W2124013616 creator A5072346979 @default.
• W2124013616 creator A5077812497 @default.
• W2124013616 creator A5084053909 @default.
• W2124013616 creator A5089073862 @default.
• W2124013616 date "2007-07-13" @default.
• W2124013616 modified "2023-10-16" @default.
• W2124013616 title "The <i>Medicago truncatula</i> DMI1 Protein Modulates Cytosolic Calcium Signaling" @default.
• W2124013616 cites W1497947649 @default.
• W2124013616 cites W1509379120 @default.
• W2124013616 cites W1576346234 @default.
• W2124013616 cites W1650401181 @default.
• W2124013616 cites W1695792414 @default.
• W2124013616 cites W1906130899 @default.
• W2124013616 cites W1967513994 @default.
• W2124013616 cites W1969641785 @default.
• W2124013616 cites W1970815708 @default.
• W2124013616 cites W1976812939 @default.
• W2124013616 cites W1982500861 @default.
• W2124013616 cites W1983147642 @default.
• W2124013616 cites W1986587865 @default.
• W2124013616 cites W2003772308 @default.
• W2124013616 cites W2003945747 @default.
• W2124013616 cites W2007961360 @default.
• W2124013616 cites W2016908474 @default.
• W2124013616 cites W2029565291 @default.
• W2124013616 cites W2034018916 @default.
• W2124013616 cites W2035855132 @default.
• W2124013616 cites W2038823160 @default.
• W2124013616 cites W2042440799 @default.
• W2124013616 cites W2043403897 @default.
• W2124013616 cites W2045095810 @default.
• W2124013616 cites W2052778278 @default.
• W2124013616 cites W2057581357 @default.
• W2124013616 cites W2062422342 @default.
• W2124013616 cites W2065121875 @default.
• W2124013616 cites W2074622988 @default.
• W2124013616 cites W2081666394 @default.
• W2124013616 cites W2085550063 @default.
• W2124013616 cites W2087074044 @default.
• W2124013616 cites W2091622541 @default.
• W2124013616 cites W2093005137 @default.
• W2124013616 cites W2101204196 @default.
• W2124013616 cites W2102897805 @default.
• W2124013616 cites W2108662839 @default.
• W2124013616 cites W2110949951 @default.
• W2124013616 cites W2113895729 @default.
• W2124013616 cites W2114115878 @default.
• W2124013616 cites W2128179874 @default.
• W2124013616 cites W2134083864 @default.
• W2124013616 cites W2138092456 @default.
• W2124013616 cites W2140948740 @default.
• W2124013616 cites W2146077744 @default.
• W2124013616 cites W2146207329 @default.
• W2124013616 cites W2154149338 @default.
• W2124013616 cites W2154315934 @default.
• W2124013616 cites W2154388712 @default.
• W2124013616 cites W2155529170 @default.
• W2124013616 cites W2156442455 @default.
• W2124013616 cites W2157275644 @default.
• W2124013616 cites W2157816691 @default.
• W2124013616 cites W70864286 @default.
• W2124013616 doi "https://doi.org/10.1104/pp.107.097261" @default.
• W2124013616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1976572" @default.
• W2124013616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17631529" @default.
• W2124013616 hasPublicationYear "2007" @default.
• W2124013616 type Work @default.
• W2124013616 sameAs 2124013616 @default.
• W2124013616 citedByCount "102" @default.
• W2124013616 countsByYear W21240136162012 @default.
• W2124013616 countsByYear W21240136162013 @default.
• W2124013616 countsByYear W21240136162014 @default.
• W2124013616 countsByYear W21240136162015 @default.
• W2124013616 countsByYear W21240136162016 @default.
• W2124013616 countsByYear W21240136162017 @default.
• W2124013616 countsByYear W21240136162018 @default.
• W2124013616 countsByYear W21240136162019 @default.
• W2124013616 countsByYear W21240136162020 @default.
• W2124013616 countsByYear W21240136162021 @default.
• W2124013616 countsByYear W21240136162022 @default.
• W2124013616 countsByYear W21240136162023 @default.
• W2124013616 crossrefType "journal-article" @default.
• W2124013616 hasAuthorship W2124013616A5012848667 @default.
• W2124013616 hasAuthorship W2124013616A5015269349 @default.
• W2124013616 hasAuthorship W2124013616A5018458414 @default.
• W2124013616 hasAuthorship W2124013616A5021534135 @default.
• W2124013616 hasAuthorship W2124013616A5027370983 @default.

• next