FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124030128> ?p ?o ?g. }

• W2124030128 endingPage "1431" @default.
• W2124030128 startingPage "1426" @default.
• W2124030128 abstract "ABSTRACT In this work, we investigated the Campylobacter jejuni dps (DNA binding protein from starved cells) gene for a role in biofilm formation and cecal colonization in poultry. In vitro biofilm formation assays were conducted with stationary-phase cells in cell culture plates under microaerophilic conditions. These studies demonstrated a significant (>50%) reduction in biofilm formation by the C. jejuni dps mutant compared to that by the wild-type strain. Studies in poultry also demonstrated the importance of the dps gene in host colonization by C. jejuni . Real-time PCR analysis of mRNA extracted from the cecal contents of poultry infected with wild-type C. jejuni indicated that the dps gene is upregulated 20-fold during poultry colonization. Cecal colonization was greater than 5 log CFU lower in chicks infected with the dps mutant than chicks infected with the wild-type C. jejuni strain. Moreover, the dps mutant failed to colonize 75% of the chicks following challenge with 10 5 CFU. Preliminary studies were conducted in chicks by parenteral vaccination with a recombinant Dps protein or through oral vaccination with a recombinant attenuated Salmonella enterica strain synthesizing the C. jejuni Dps protein. No reduction in C. jejuni was noted in chicks vaccinated with the parenteral recombinant protein, whereas, a 2.5-log-unit reduction of C. jejuni was achieved in chicks vaccinated with the attenuated Salmonella vector after homologous challenge. Taken together, this work demonstrated the importance of Dps for biofilm formation and poultry colonization, and the study also provides a basis for continued work using the Dps protein as a vaccine antigen when delivered through a Salmonella vaccine vector." @default.
• W2124030128 created "2016-06-24" @default.
• W2124030128 creator A5011118108 @default.
• W2124030128 creator A5014007186 @default.
• W2124030128 creator A5035189002 @default.
• W2124030128 creator A5035800331 @default.
• W2124030128 creator A5038727730 @default.
• W2124030128 creator A5044344943 @default.
• W2124030128 creator A5071791295 @default.
• W2124030128 date "2012-09-01" @default.
• W2124030128 modified "2023-10-17" @default.
• W2124030128 title "The Campylobacter jejuni Dps Homologue Is Important for <i>In Vitro</i> Biofilm Formation and Cecal Colonization of Poultry and May Serve as a Protective Antigen for Vaccination" @default.
• W2124030128 cites W1554968268 @default.
• W2124030128 cites W1569777122 @default.
• W2124030128 cites W1968487526 @default.
• W2124030128 cites W1981926846 @default.
• W2124030128 cites W1982534772 @default.
• W2124030128 cites W1989084104 @default.
• W2124030128 cites W2001282251 @default.
• W2124030128 cites W2008989704 @default.
• W2124030128 cites W2040417344 @default.
• W2124030128 cites W2045743979 @default.
• W2124030128 cites W2048622484 @default.
• W2124030128 cites W2064348965 @default.
• W2124030128 cites W2088800726 @default.
• W2124030128 cites W2089058761 @default.
• W2124030128 cites W2096743942 @default.
• W2124030128 cites W2097011626 @default.
• W2124030128 cites W2097235809 @default.
• W2124030128 cites W2100837269 @default.
• W2124030128 cites W2101220987 @default.
• W2124030128 cites W2103823054 @default.
• W2124030128 cites W2105437718 @default.
• W2124030128 cites W2108244474 @default.
• W2124030128 cites W2109248840 @default.
• W2124030128 cites W2128591134 @default.
• W2124030128 cites W2131727615 @default.
• W2124030128 cites W2137058189 @default.
• W2124030128 cites W2137182736 @default.
• W2124030128 cites W2140598855 @default.
• W2124030128 cites W2145336455 @default.
• W2124030128 cites W2148217835 @default.
• W2124030128 cites W2151490489 @default.
• W2124030128 cites W2158284941 @default.
• W2124030128 cites W2163469003 @default.
• W2124030128 cites W4238469206 @default.
• W2124030128 doi "https://doi.org/10.1128/cvi.00151-12" @default.
• W2124030128 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3428391" @default.
• W2124030128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22787197" @default.
• W2124030128 hasPublicationYear "2012" @default.
• W2124030128 type Work @default.
• W2124030128 sameAs 2124030128 @default.
• W2124030128 citedByCount "62" @default.
• W2124030128 countsByYear W21240301282013 @default.
• W2124030128 countsByYear W21240301282014 @default.
• W2124030128 countsByYear W21240301282015 @default.
• W2124030128 countsByYear W21240301282016 @default.
• W2124030128 countsByYear W21240301282017 @default.
• W2124030128 countsByYear W21240301282018 @default.
• W2124030128 countsByYear W21240301282019 @default.
• W2124030128 countsByYear W21240301282020 @default.
• W2124030128 countsByYear W21240301282021 @default.
• W2124030128 countsByYear W21240301282022 @default.
• W2124030128 countsByYear W21240301282023 @default.
• W2124030128 crossrefType "journal-article" @default.
• W2124030128 hasAuthorship W2124030128A5011118108 @default.
• W2124030128 hasAuthorship W2124030128A5014007186 @default.
• W2124030128 hasAuthorship W2124030128A5035189002 @default.
• W2124030128 hasAuthorship W2124030128A5035800331 @default.
• W2124030128 hasAuthorship W2124030128A5038727730 @default.
• W2124030128 hasAuthorship W2124030128A5044344943 @default.
• W2124030128 hasAuthorship W2124030128A5071791295 @default.
• W2124030128 hasBestOaLocation W21240301281 @default.
• W2124030128 hasConcept C104317684 @default.
• W2124030128 hasConcept C105702510 @default.
• W2124030128 hasConcept C143065580 @default.
• W2124030128 hasConcept C159047783 @default.
• W2124030128 hasConcept C22070199 @default.
• W2124030128 hasConcept C2776927270 @default.
• W2124030128 hasConcept C2776957140 @default.
• W2124030128 hasConcept C2778022156 @default.
• W2124030128 hasConcept C2779607309 @default.
• W2124030128 hasConcept C2779910956 @default.
• W2124030128 hasConcept C2781065037 @default.
• W2124030128 hasConcept C40767141 @default.
• W2124030128 hasConcept C523546767 @default.
• W2124030128 hasConcept C54355233 @default.
• W2124030128 hasConcept C58123911 @default.
• W2124030128 hasConcept C86803240 @default.
• W2124030128 hasConcept C89423630 @default.
• W2124030128 hasConceptScore W2124030128C104317684 @default.
• W2124030128 hasConceptScore W2124030128C105702510 @default.
• W2124030128 hasConceptScore W2124030128C143065580 @default.
• W2124030128 hasConceptScore W2124030128C159047783 @default.
• W2124030128 hasConceptScore W2124030128C22070199 @default.
• W2124030128 hasConceptScore W2124030128C2776927270 @default.
• W2124030128 hasConceptScore W2124030128C2776957140 @default.
• W2124030128 hasConceptScore W2124030128C2778022156 @default.

• next