FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124103764> ?p ?o ?g. }

• W2124103764 endingPage "2120" @default.
• W2124103764 startingPage "2109" @default.
• W2124103764 abstract "Abstract The amount of inorganic carbon represents one of the main environmental factors determining productivity of photoautotrophic organisms. Using the model cyanobacterium Synechocystis sp. PCC 6803, we performed a first metabolome study with cyanobacterial cells shifted from high CO2 (5% in air) into conditions of low CO2 (LC; ambient air with 0.035% CO2). Using gas chromatography-mass spectrometry, 74 metabolites were reproducibly identified under different growth conditions. Shifting wild-type cells into LC conditions resulted in a global metabolic reprogramming and involved increases of, for example, 2-oxoglutarate (2OG) and phosphoenolpyruvate, and reductions of, for example, sucrose and fructose-1,6-bisphosphate. A decrease in Calvin-Benson cycle activity and increased usage of associated carbon cycling routes, including photorespiratory metabolism, was indicated by synergistic accumulation of the fumarate, malate, and 2-phosphoglycolate pools and a transient increase of 3-phosphoglycerate. The unexpected accumulation of 2OG with a concomitant decrease of glutamine pointed toward reduced nitrogen availability when cells are confronted with LC. Despite the increase in 2OG and low amino acid pools, we found a complete dephosphorylation of the PII regulatory protein at LC characteristic for nitrogen-replete conditions. Moreover, mutants with defined blocks in the photorespiratory metabolism leading to the accumulation of glycolate and glycine, respectively, exhibited features of LC-treated wild-type cells such as the changed 2OG to glutamine ratio and PII phosphorylation state already under high CO2 conditions. Thus, metabolome profiling demonstrated that acclimation to LC involves coordinated changes of carbon and interacting nitrogen metabolism. We hypothesize that Synechocystis has a temporal lag of acclimating carbon versus nitrogen metabolism with carbon leading." @default.
• W2124103764 created "2016-06-24" @default.
• W2124103764 creator A5004800476 @default.
• W2124103764 creator A5051590888 @default.
• W2124103764 creator A5063176250 @default.
• W2124103764 creator A5073438755 @default.
• W2124103764 creator A5082558655 @default.
• W2124103764 creator A5086536131 @default.
• W2124103764 date "2008-10-22" @default.
• W2124103764 modified "2023-10-11" @default.
• W2124103764 title "Metabolome Phenotyping of Inorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium <i>Synechocystis</i> sp. Strain PCC 6803" @default.
• W2124103764 cites W145473912 @default.
• W2124103764 cites W1490314836 @default.
• W2124103764 cites W1509926796 @default.
• W2124103764 cites W1549912426 @default.
• W2124103764 cites W1643288909 @default.
• W2124103764 cites W1966203257 @default.
• W2124103764 cites W1966947548 @default.
• W2124103764 cites W1977920620 @default.
• W2124103764 cites W1985708845 @default.
• W2124103764 cites W2005503359 @default.
• W2124103764 cites W2011575924 @default.
• W2124103764 cites W2012178637 @default.
• W2124103764 cites W2013191289 @default.
• W2124103764 cites W2016383559 @default.
• W2124103764 cites W2032699062 @default.
• W2124103764 cites W2038295777 @default.
• W2124103764 cites W2044365082 @default.
• W2124103764 cites W2044977893 @default.
• W2124103764 cites W2076827307 @default.
• W2124103764 cites W2090798322 @default.
• W2124103764 cites W2093131891 @default.
• W2124103764 cites W2095071775 @default.
• W2124103764 cites W2102992921 @default.
• W2124103764 cites W2104263415 @default.
• W2124103764 cites W2115798649 @default.
• W2124103764 cites W2115863196 @default.
• W2124103764 cites W2134218591 @default.
• W2124103764 cites W2140047239 @default.
• W2124103764 cites W2148632523 @default.
• W2124103764 cites W2149545078 @default.
• W2124103764 cites W2149928591 @default.
• W2124103764 cites W2151346683 @default.
• W2124103764 cites W2156723754 @default.
• W2124103764 cites W2156725813 @default.
• W2124103764 cites W2159593664 @default.
• W2124103764 cites W2160763722 @default.
• W2124103764 cites W2161390102 @default.
• W2124103764 cites W2168617775 @default.
• W2124103764 cites W2170751345 @default.
• W2124103764 cites W2415111517 @default.
• W2124103764 cites W45534775 @default.
• W2124103764 doi "https://doi.org/10.1104/pp.108.129403" @default.
• W2124103764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2593672" @default.
• W2124103764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18945936" @default.
• W2124103764 hasPublicationYear "2008" @default.
• W2124103764 type Work @default.
• W2124103764 sameAs 2124103764 @default.
• W2124103764 citedByCount "79" @default.
• W2124103764 countsByYear W21241037642012 @default.
• W2124103764 countsByYear W21241037642013 @default.
• W2124103764 countsByYear W21241037642014 @default.
• W2124103764 countsByYear W21241037642015 @default.
• W2124103764 countsByYear W21241037642016 @default.
• W2124103764 countsByYear W21241037642017 @default.
• W2124103764 countsByYear W21241037642018 @default.
• W2124103764 countsByYear W21241037642019 @default.
• W2124103764 countsByYear W21241037642020 @default.
• W2124103764 countsByYear W21241037642021 @default.
• W2124103764 countsByYear W21241037642022 @default.
• W2124103764 countsByYear W21241037642023 @default.
• W2124103764 crossrefType "journal-article" @default.
• W2124103764 hasAuthorship W2124103764A5004800476 @default.
• W2124103764 hasAuthorship W2124103764A5051590888 @default.
• W2124103764 hasAuthorship W2124103764A5063176250 @default.
• W2124103764 hasAuthorship W2124103764A5073438755 @default.
• W2124103764 hasAuthorship W2124103764A5082558655 @default.
• W2124103764 hasAuthorship W2124103764A5086536131 @default.
• W2124103764 hasBestOaLocation W21241037641 @default.
• W2124103764 hasConcept C104317684 @default.
• W2124103764 hasConcept C135870905 @default.
• W2124103764 hasConcept C143065580 @default.
• W2124103764 hasConcept C143937172 @default.
• W2124103764 hasConcept C185592680 @default.
• W2124103764 hasConcept C207583985 @default.
• W2124103764 hasConcept C2777477808 @default.
• W2124103764 hasConcept C2777756961 @default.
• W2124103764 hasConcept C2778597767 @default.
• W2124103764 hasConcept C2779349466 @default.
• W2124103764 hasConcept C2779669040 @default.
• W2124103764 hasConcept C2780238584 @default.
• W2124103764 hasConcept C515207424 @default.
• W2124103764 hasConcept C523546767 @default.
• W2124103764 hasConcept C54355233 @default.
• W2124103764 hasConcept C55493867 @default.
• W2124103764 hasConcept C62231903 @default.
• W2124103764 hasConcept C86803240 @default.
• W2124103764 hasConceptScore W2124103764C104317684 @default.

• next