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- W2124117788 abstract "Multidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge over two decades ago. The worldwide spread of methicillin-resistant Staphylococcus aureus (MRSA), glycopeptide-resistant enterococci and other resistant Gram-positive pathogens had a major impact on antibiotic policies, and prompted the discovery and development of new antibiotics to combat difficult-to-treat infections caused by such pathogens. Several new antibiotics active against multidrug-resistant Gram-positive pathogens have recently been introduced into clinical practice, and the antibiotic pipeline contains additional anti-Gram-positive drugs at an advanced stage of development, including new glycopeptides (dalbavancin, oritavancin, and telavancin), new anti-MRSA β-lactams (ceftobiprole), and new diaminopyrimidines (iclaprim). This article provides a brief overview of these upcoming agents, partially based on the material presented at the ESCMID Conference entitled ‘Fighting infections due to multidrug-resistant Gram-positives’ (Venice, Italy, 29–31 May 2008) and on the most recent literature." @default.
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- W2124117788 date "2009-03-01" @default.
- W2124117788 modified "2023-10-17" @default.
- W2124117788 title "Forthcoming therapeutic perspectives for infections due to multidrug-resistant Gram-positive pathogens" @default.
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- W2124117788 doi "https://doi.org/10.1111/j.1469-0691.2009.02740.x" @default.
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