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• W2124131796 abstract "Glucagon-like peptide 1 (GLP-1) is both a gut-derived hormone and a neurotransmitter synthesized in the brain. Early reports suggested that GLP-1 acts in the periphery to promote insulin secretion and affect glucose homeostasis, whereas central GLP-1 reduces food intake and body weight. However, current research indicates that in fact, GLP-1 in each location plays a role in these functions. This review summarizes the evidence for involvement of peripheral and brain GLP-1 in food intake regulation and glucose homeostasis and proposes a model for the coordinated actions of GLP-1 at multiple sites." @default.
• W2124131796 created "2016-06-24" @default.
• W2124131796 creator A5053625751 @default.
• W2124131796 date "2009-04-23" @default.
• W2124131796 modified "2023-09-25" @default.
• W2124131796 title "Minireview: Finding the Sweet Spot: Peripheral Versus Central Glucagon-Like Peptide 1 Action in Feeding and Glucose Homeostasis" @default.
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• W2124131796 doi "https://doi.org/10.1210/en.2009-0220" @default.
• W2124131796 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2703557" @default.
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