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• W2124174283 abstract "Articular cartilage has limited regenerative capabilities. Chondrocytes from different layers of cartilage have specific properties, and regenerative approaches using zonal chondrocytes may yield better replication of the architecture of native cartilage than when using a single cell population. To obtain high seeding efficiency while still mimicking zonal architecture, cell pellets of expanded deep zone and superficial zone equine chondrocytes were seeded and cultured in two layers on poly(ethylene glycol)-terephthalate-poly(butylene terephthalate) (PEGT-PBT) scaffolds. Scaffolds seeded with cell pellets consisting of a 1:1 mixture of both cell sources served as controls. Parallel to this, pellets of superficial or deep zone chondrocytes, and combinations of the two cell populations, were cultured without the scaffold. Pellet cultures of zonal chondrocytes in scaffolds resulted in a high seeding efficiency and abundant cartilaginous tissue formation, containing collagen type II and glycosaminoglycans (GAGs) in all groups, irrespective of the donor (n = 3), zonal population or stratified scaffold-seeding approach used. However, whereas total GAG production was similar, the constructs retained significantly more GAG compared to pellet cultures, in which a high percentage of the produced GAGs were secreted into the culture medium. Immunohistochemistry for zonal markers did not show any differences between the conditions. We conclude that spatially defined pellet culture in 3D scaffolds is associated with high seeding efficiency and supports cartilaginous tissue formation, but did not result in the maintenance or restoration of the original zonal phenotype. The use of pellet-assembled constructs leads to a better retainment of newly produced GAGs than the use of pellet cultures alone." @default.
• W2124174283 created "2016-06-24" @default.
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• W2124174283 date "2013-04-18" @default.
• W2124174283 modified "2023-09-23" @default.
• W2124174283 title "Three-dimensional assembly of tissue-engineered cartilage constructs results in cartilaginous tissue formation without retainment of zonal characteristics" @default.
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• W2124174283 cites W1969172986 @default.
• W2124174283 cites W1974694084 @default.
• W2124174283 cites W1976883962 @default.
• W2124174283 cites W1979169277 @default.
• W2124174283 cites W1983617872 @default.
• W2124174283 cites W1984403034 @default.
• W2124174283 cites W1984896996 @default.
• W2124174283 cites W1986902239 @default.
• W2124174283 cites W1989995073 @default.
• W2124174283 cites W1992630810 @default.
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• W2124174283 cites W1997429641 @default.
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• W2124174283 cites W1999512926 @default.
• W2124174283 cites W2000806212 @default.
• W2124174283 cites W2001705900 @default.
• W2124174283 cites W2007055685 @default.
• W2124174283 cites W2014641370 @default.
• W2124174283 cites W2014910209 @default.
• W2124174283 cites W2017360130 @default.
• W2124174283 cites W2026458998 @default.
• W2124174283 cites W2026812028 @default.
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• W2124174283 cites W2032130576 @default.
• W2124174283 cites W2032255522 @default.
• W2124174283 cites W2033577358 @default.
• W2124174283 cites W2037023035 @default.
• W2124174283 cites W2040984241 @default.
• W2124174283 cites W2041072341 @default.
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• W2124174283 cites W2083994991 @default.
• W2124174283 cites W2091135611 @default.
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• W2124174283 doi "https://doi.org/10.1002/term.1726" @default.
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