FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124180846> ?p ?o ?g. }

• W2124180846 abstract "West Nile Virus (WNV) is a mosquito-borne flavivirus that has caused ongoing seasonal epidemics in the United States since 1999. It is estimated that ≤1% of WNV-infected patients will develop neuroinvasive disease (West Nile encephalitis and/or myelitis) that can result in debilitating morbidities and long-term sequelae. It is essential to collect longitudinal information about the recovery process and to characterize predicative factors that may assist in therapeutic decision-making in the future.We report a longitudinal study of the neurological outcomes (as measured by neurological examination, Glascow Coma Scale, and Modified Mini-Mental State Examination) for 55 subjects with WNV neuroinvasive disease (confirmed by positive CSF IgM) assessed on day 7, at discharge, and on days 14, 30, and 90. The neurological outcome measures were coma (presence and degree), global cognitive status, presence of cranial neuropathy, tremors and/or weakness.At initial clinical presentation 93% presented with a significant neurological deficit (49% with weakness, 35% with tremor, and 16% with cranial neuropathy). The number of patients with a cognitive deficit fell from 25 at initial evaluation to 9 at their last evaluation. Cranial neuropathy was present in 9 at onset and in only 4 patients at study conclusion. Of the 19 patients who had a tremor at enrollment, 11 continued to exhibit a tremor at follow-up. Seven patients died after initial enrollment in the study, with 5 of those having presented in a coma. The factors that predict either severity or long-term recovery of neurological function include age (older individuals were weaker at follow-up examination), gender (males recovered better from coma), and presentation in a coma with cranial nerve deficits (had a poorer recovery particularly with regard to cognition).This study represents one of the largest clinical investigations providing prospectively-acquired neurological outcomes data among American patients with WNV central nervous system disease. The findings show that the factors that influence prognosis from the initial presentation include age, gender, and specific neurological deficits at onset.ClinicalTrials.gov identifier: NCT00138463 and NCT00069316." @default.
• W2124180846 created "2016-06-24" @default.
• W2124180846 creator A5022962189 @default.
• W2124180846 creator A5022971416 @default.
• W2124180846 creator A5023104005 @default.
• W2124180846 creator A5023687317 @default.
• W2124180846 creator A5031398889 @default.
• W2124180846 creator A5040153216 @default.
• W2124180846 creator A5044212537 @default.
• W2124180846 creator A5064559286 @default.
• W2124180846 creator A5082107467 @default.
• W2124180846 creator A5089547586 @default.
• W2124180846 date "2014-05-09" @default.
• W2124180846 modified "2023-10-10" @default.
• W2124180846 title "West Nile virus neuroinvasive disease: neurological manifestations and prospective longitudinal outcomes" @default.
• W2124180846 cites W174726270 @default.
• W2124180846 cites W1973680902 @default.
• W2124180846 cites W1990019351 @default.
• W2124180846 cites W1999732999 @default.
• W2124180846 cites W2001406632 @default.
• W2124180846 cites W2003980781 @default.
• W2124180846 cites W2005549185 @default.
• W2124180846 cites W2014224963 @default.
• W2124180846 cites W2033969877 @default.
• W2124180846 cites W2035851939 @default.
• W2124180846 cites W2038290472 @default.
• W2124180846 cites W2057185280 @default.
• W2124180846 cites W2059254211 @default.
• W2124180846 cites W2061053192 @default.
• W2124180846 cites W2068185438 @default.
• W2124180846 cites W2072176481 @default.
• W2124180846 cites W2073547844 @default.
• W2124180846 cites W2073615594 @default.
• W2124180846 cites W2084926821 @default.
• W2124180846 cites W2101559962 @default.
• W2124180846 cites W2109504587 @default.
• W2124180846 cites W2118911422 @default.
• W2124180846 cites W2143861314 @default.
• W2124180846 cites W2159889994 @default.
• W2124180846 cites W2312900551 @default.
• W2124180846 doi "https://doi.org/10.1186/1471-2334-14-248" @default.
• W2124180846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4020876" @default.
• W2124180846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24884681" @default.
• W2124180846 hasPublicationYear "2014" @default.
• W2124180846 type Work @default.
• W2124180846 sameAs 2124180846 @default.
• W2124180846 citedByCount "89" @default.
• W2124180846 countsByYear W21241808462014 @default.
• W2124180846 countsByYear W21241808462015 @default.
• W2124180846 countsByYear W21241808462016 @default.
• W2124180846 countsByYear W21241808462017 @default.
• W2124180846 countsByYear W21241808462018 @default.
• W2124180846 countsByYear W21241808462019 @default.
• W2124180846 countsByYear W21241808462020 @default.
• W2124180846 countsByYear W21241808462021 @default.
• W2124180846 countsByYear W21241808462022 @default.
• W2124180846 countsByYear W21241808462023 @default.
• W2124180846 crossrefType "journal-article" @default.
• W2124180846 hasAuthorship W2124180846A5022962189 @default.
• W2124180846 hasAuthorship W2124180846A5022971416 @default.
• W2124180846 hasAuthorship W2124180846A5023104005 @default.
• W2124180846 hasAuthorship W2124180846A5023687317 @default.
• W2124180846 hasAuthorship W2124180846A5031398889 @default.
• W2124180846 hasAuthorship W2124180846A5040153216 @default.
• W2124180846 hasAuthorship W2124180846A5044212537 @default.
• W2124180846 hasAuthorship W2124180846A5064559286 @default.
• W2124180846 hasAuthorship W2124180846A5082107467 @default.
• W2124180846 hasAuthorship W2124180846A5089547586 @default.
• W2124180846 hasBestOaLocation W21241808461 @default.
• W2124180846 hasConcept C100136789 @default.
• W2124180846 hasConcept C118552586 @default.
• W2124180846 hasConcept C120665830 @default.
• W2124180846 hasConcept C121332964 @default.
• W2124180846 hasConcept C126322002 @default.
• W2124180846 hasConcept C141071460 @default.
• W2124180846 hasConcept C142724271 @default.
• W2124180846 hasConcept C16568411 @default.
• W2124180846 hasConcept C17624336 @default.
• W2124180846 hasConcept C187212893 @default.
• W2124180846 hasConcept C2777895361 @default.
• W2124180846 hasConcept C2779134260 @default.
• W2124180846 hasConcept C2780168130 @default.
• W2124180846 hasConcept C2780247198 @default.
• W2124180846 hasConcept C71924100 @default.
• W2124180846 hasConceptScore W2124180846C100136789 @default.
• W2124180846 hasConceptScore W2124180846C118552586 @default.
• W2124180846 hasConceptScore W2124180846C120665830 @default.
• W2124180846 hasConceptScore W2124180846C121332964 @default.
• W2124180846 hasConceptScore W2124180846C126322002 @default.
• W2124180846 hasConceptScore W2124180846C141071460 @default.
• W2124180846 hasConceptScore W2124180846C142724271 @default.
• W2124180846 hasConceptScore W2124180846C16568411 @default.
• W2124180846 hasConceptScore W2124180846C17624336 @default.
• W2124180846 hasConceptScore W2124180846C187212893 @default.
• W2124180846 hasConceptScore W2124180846C2777895361 @default.
• W2124180846 hasConceptScore W2124180846C2779134260 @default.
• W2124180846 hasConceptScore W2124180846C2780168130 @default.
• W2124180846 hasConceptScore W2124180846C2780247198 @default.
• W2124180846 hasConceptScore W2124180846C71924100 @default.
• W2124180846 hasIssue "1" @default.

• next