FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124186735> ?p ?o ?g. }

• W2124186735 endingPage "471" @default.
• W2124186735 startingPage "457" @default.
• W2124186735 abstract "Irritation of the eyes, nose, and throat by airborne chemicals—also referred to as “sensory irritation”—is an important endpoint in both occupational and environmental toxicology. Modeling of human sensory irritation relies on knowledge of the physical chemistry of the compound(s) involved, as well as the exposure parameters (concentration and duration). A reciprocal relationship between these two exposure variables is postulated under Haber's law, implying that protracted, low-level exposures may be toxicologically equivalent to brief, high-level exposures. Although time is recognized as having an influence on sensory irritation, the quantitative predictions of Haber's Law have been addressed for only a handful of compounds in human experimental studies. We have conducted a systematic literature review that includes a semiquantitative comparison of psychophysical data extracted from controlled human exposure studies versus. the predictions of Haber's law. Studies containing relevant data involved exposures to ammonia (2), chlorine (2), formaldehyde (1), inorganic dusts such as calcium oxide (1), and the volatile organic compound 1-octene (1). With the exception of dust exposure, varying exposure concentration has a proportionally greater effect on sensory irritation than does changing exposure duration. For selected time windows, a more generalized power law model (cn × t = k) rather than Haber's law per se (c × t = k) yields reasonably robust predictions. Complicating this picture, however, is the frequent observation of intensity–time “plateauing,” with time effects disappearing, or even reversing, after a relatively short period, depending on the test compound. The implications of these complex temporal dynamics for risk assessment and standard setting have been incompletely explored to date." @default.
• W2124186735 created "2016-06-24" @default.
• W2124186735 creator A5011328276 @default.
• W2124186735 creator A5020959035 @default.
• W2124186735 creator A5066613099 @default.
• W2124186735 date "2006-01-01" @default.
• W2124186735 modified "2023-10-17" @default.
• W2124186735 title "Does Haber's Law Apply to Human Sensory Irritation?" @default.
• W2124186735 cites W1820267547 @default.
• W2124186735 cites W1883044208 @default.
• W2124186735 cites W1969329552 @default.
• W2124186735 cites W1977463987 @default.
• W2124186735 cites W1977723479 @default.
• W2124186735 cites W1985651715 @default.
• W2124186735 cites W1989366671 @default.
• W2124186735 cites W1989786547 @default.
• W2124186735 cites W1997682426 @default.
• W2124186735 cites W2001900688 @default.
• W2124186735 cites W2011862135 @default.
• W2124186735 cites W2016869592 @default.
• W2124186735 cites W2020473873 @default.
• W2124186735 cites W2029654180 @default.
• W2124186735 cites W2034977259 @default.
• W2124186735 cites W2036330482 @default.
• W2124186735 cites W2037298897 @default.
• W2124186735 cites W2044321330 @default.
• W2124186735 cites W2046094021 @default.
• W2124186735 cites W2046920780 @default.
• W2124186735 cites W2049547145 @default.
• W2124186735 cites W2050540644 @default.
• W2124186735 cites W2055434434 @default.
• W2124186735 cites W2060060791 @default.
• W2124186735 cites W2061676245 @default.
• W2124186735 cites W2065590344 @default.
• W2124186735 cites W2067282768 @default.
• W2124186735 cites W2075898463 @default.
• W2124186735 cites W2093310041 @default.
• W2124186735 cites W2095806781 @default.
• W2124186735 cites W2104018344 @default.
• W2124186735 cites W2105081649 @default.
• W2124186735 cites W2116339181 @default.
• W2124186735 cites W2120969940 @default.
• W2124186735 cites W2127383908 @default.
• W2124186735 cites W2129729924 @default.
• W2124186735 cites W2136775007 @default.
• W2124186735 cites W2145077191 @default.
• W2124186735 cites W2146200347 @default.
• W2124186735 cites W2146530776 @default.
• W2124186735 cites W2152744415 @default.
• W2124186735 cites W2152907732 @default.
• W2124186735 cites W2154036312 @default.
• W2124186735 cites W2156924542 @default.
• W2124186735 cites W2167058705 @default.
• W2124186735 cites W2168701820 @default.
• W2124186735 cites W2323174359 @default.
• W2124186735 cites W2328925473 @default.
• W2124186735 cites W3142370138 @default.
• W2124186735 cites W4247196243 @default.
• W2124186735 cites W4253631879 @default.
• W2124186735 cites W4302216680 @default.
• W2124186735 doi "https://doi.org/10.1080/08958370600602322" @default.
• W2124186735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16603477" @default.
• W2124186735 hasPublicationYear "2006" @default.
• W2124186735 type Work @default.
• W2124186735 sameAs 2124186735 @default.
• W2124186735 citedByCount "36" @default.
• W2124186735 countsByYear W21241867352012 @default.
• W2124186735 countsByYear W21241867352013 @default.
• W2124186735 countsByYear W21241867352014 @default.
• W2124186735 countsByYear W21241867352015 @default.
• W2124186735 countsByYear W21241867352016 @default.
• W2124186735 countsByYear W21241867352017 @default.
• W2124186735 countsByYear W21241867352018 @default.
• W2124186735 countsByYear W21241867352020 @default.
• W2124186735 countsByYear W21241867352021 @default.
• W2124186735 countsByYear W21241867352022 @default.
• W2124186735 countsByYear W21241867352023 @default.
• W2124186735 crossrefType "journal-article" @default.
• W2124186735 hasAuthorship W2124186735A5011328276 @default.
• W2124186735 hasAuthorship W2124186735A5020959035 @default.
• W2124186735 hasAuthorship W2124186735A5066613099 @default.
• W2124186735 hasConcept C185592680 @default.
• W2124186735 hasConcept C203014093 @default.
• W2124186735 hasConcept C2777063393 @default.
• W2124186735 hasConcept C2994251472 @default.
• W2124186735 hasConcept C3019635159 @default.
• W2124186735 hasConcept C71924100 @default.
• W2124186735 hasConcept C99454951 @default.
• W2124186735 hasConceptScore W2124186735C185592680 @default.
• W2124186735 hasConceptScore W2124186735C203014093 @default.
• W2124186735 hasConceptScore W2124186735C2777063393 @default.
• W2124186735 hasConceptScore W2124186735C2994251472 @default.
• W2124186735 hasConceptScore W2124186735C3019635159 @default.
• W2124186735 hasConceptScore W2124186735C71924100 @default.
• W2124186735 hasConceptScore W2124186735C99454951 @default.
• W2124186735 hasIssue "7" @default.
• W2124186735 hasLocation W21241867351 @default.
• W2124186735 hasLocation W21241867352 @default.

• next