FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124238464> ?p ?o ?g. }

• W2124238464 endingPage "271" @default.
• W2124238464 startingPage "266" @default.
• W2124238464 abstract "Coronary occlusive disease is the major long-term complication after cardiac transplantation. The relation between minor angiographic abnormalities and myocardial perfusion has not been previously assessed in a large number of cardiac transplant patients.Prospective study. Coronary flow reserve was measured with an intracoronary Doppler flow probe in the proximal left anterior descending coronary artery in each patient. A dose of intracoronary papaverine producing maximal vasodilation was then administered.A regional cardiothoracic centre and a supraregional transplant unit.Seven patients with chest pain but normal coronary anatomy (controls), and 61 cardiac transplant patients between three months and 10 years after operation (median 4.5 years). Twenty one cardiac transplant patients had angiographic evidence of minor coronary occlusive disease (mean (SD) percentage stenosis diameter 23% (6%)) in a primary or secondary coronary vessel (group 1), with 12 of these in the left anterior descending coronary artery (stenosis diameter (mean (SD) 24% (8%)). The remaining 40 transplant patients had normal coronary angiograms (group 2).Coronary flow reserve was defined as the ratio of the peak flow velocity after papaverine to the resting flow velocity.Group 1 patients had a noticeably impaired coronary flow reserve (2.6 (1.1)) compared with control patients (3.9 (0.4), p = 0.05) and, after adjusting for year after operation, compared with group 2 patients (3.8 (1.0), p < 0.001). No other variables were associated with a reduction in coronary flow reserve. Mean resting flow velocity was similar in all three groups (controls, 7.4 (4.6) cm/s; group 1, 7.5 (5.9) cm/s; and group 2, 7.3 (3.9) cm/s). Mean peak flow velocity response to papaverine was reduced in group 1 patients (18.1 (13.5) cm/s) relative to group 2 patients (27.5 (15.4) cm/s, p = 0.05) but not controls (28.4 (15.1) cm/s, p = 0.1).Coronary flow reserve and the peak flow response to the coronary vascular smooth muscle relaxant papaverine are impaired in cardiac transplant patients with minor coronary occlusive disease. This disturbance of cardiac microvascular function may contribute to the late morbidity and mortality seen in cardiac transplant patients with coronary occlusive disease." @default.
• W2124238464 created "2016-06-24" @default.
• W2124238464 creator A5006979396 @default.
• W2124238464 creator A5024608079 @default.
• W2124238464 creator A5046014607 @default.
• W2124238464 creator A5047557503 @default.
• W2124238464 creator A5053806008 @default.
• W2124238464 creator A5064415116 @default.
• W2124238464 creator A5064491710 @default.
• W2124238464 date "1992-09-01" @default.
• W2124238464 modified "2023-09-25" @default.
• W2124238464 title "Impairment of coronary flow reserve in orthotopic cardiac transplant recipients with minor coronary occlusive disease" @default.
• W2124238464 cites W109090962 @default.
• W2124238464 cites W1970003185 @default.
• W2124238464 cites W1971132849 @default.
• W2124238464 cites W1974595603 @default.
• W2124238464 cites W1976098142 @default.
• W2124238464 cites W1983322810 @default.
• W2124238464 cites W1998866341 @default.
• W2124238464 cites W20079048 @default.
• W2124238464 cites W2020506085 @default.
• W2124238464 cites W2024803868 @default.
• W2124238464 cites W2035285278 @default.
• W2124238464 cites W2035610186 @default.
• W2124238464 cites W2055044704 @default.
• W2124238464 cites W2069828020 @default.
• W2124238464 cites W2076635077 @default.
• W2124238464 cites W2077935074 @default.
• W2124238464 cites W2085612839 @default.
• W2124238464 cites W2102067041 @default.
• W2124238464 cites W2103214510 @default.
• W2124238464 cites W2114075838 @default.
• W2124238464 cites W2171960414 @default.
• W2124238464 cites W2411493934 @default.
• W2124238464 cites W2413390155 @default.
• W2124238464 cites W2416492270 @default.
• W2124238464 cites W2424796634 @default.
• W2124238464 cites W2465163847 @default.
• W2124238464 cites W2474567508 @default.
• W2124238464 cites W4249894851 @default.
• W2124238464 cites W4255940022 @default.
• W2124238464 doi "https://doi.org/10.1136/hrt.68.9.266" @default.
• W2124238464 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1025068" @default.
• W2124238464 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1389756" @default.
• W2124238464 hasPublicationYear "1992" @default.
• W2124238464 type Work @default.
• W2124238464 sameAs 2124238464 @default.
• W2124238464 citedByCount "38" @default.
• W2124238464 countsByYear W21242384642012 @default.
• W2124238464 countsByYear W21242384642013 @default.
• W2124238464 countsByYear W21242384642014 @default.
• W2124238464 countsByYear W21242384642015 @default.
• W2124238464 crossrefType "journal-article" @default.
• W2124238464 hasAuthorship W2124238464A5006979396 @default.
• W2124238464 hasAuthorship W2124238464A5024608079 @default.
• W2124238464 hasAuthorship W2124238464A5046014607 @default.
• W2124238464 hasAuthorship W2124238464A5047557503 @default.
• W2124238464 hasAuthorship W2124238464A5053806008 @default.
• W2124238464 hasAuthorship W2124238464A5064415116 @default.
• W2124238464 hasAuthorship W2124238464A5064491710 @default.
• W2124238464 hasBestOaLocation W21242384641 @default.
• W2124238464 hasConcept C126322002 @default.
• W2124238464 hasConcept C158846371 @default.
• W2124238464 hasConcept C164705383 @default.
• W2124238464 hasConcept C2776157398 @default.
• W2124238464 hasConcept C2776952824 @default.
• W2124238464 hasConcept C2778213512 @default.
• W2124238464 hasConcept C2778704086 @default.
• W2124238464 hasConcept C2778707443 @default.
• W2124238464 hasConcept C2780007028 @default.
• W2124238464 hasConcept C71924100 @default.
• W2124238464 hasConceptScore W2124238464C126322002 @default.
• W2124238464 hasConceptScore W2124238464C158846371 @default.
• W2124238464 hasConceptScore W2124238464C164705383 @default.
• W2124238464 hasConceptScore W2124238464C2776157398 @default.
• W2124238464 hasConceptScore W2124238464C2776952824 @default.
• W2124238464 hasConceptScore W2124238464C2778213512 @default.
• W2124238464 hasConceptScore W2124238464C2778704086 @default.
• W2124238464 hasConceptScore W2124238464C2778707443 @default.
• W2124238464 hasConceptScore W2124238464C2780007028 @default.
• W2124238464 hasConceptScore W2124238464C71924100 @default.
• W2124238464 hasIssue "9" @default.
• W2124238464 hasLocation W21242384641 @default.
• W2124238464 hasLocation W21242384642 @default.
• W2124238464 hasLocation W21242384643 @default.
• W2124238464 hasLocation W21242384644 @default.
• W2124238464 hasOpenAccess W2124238464 @default.
• W2124238464 hasPrimaryLocation W21242384641 @default.
• W2124238464 hasRelatedWork W116287898 @default.
• W2124238464 hasRelatedWork W1983882276 @default.
• W2124238464 hasRelatedWork W2049231558 @default.
• W2124238464 hasRelatedWork W2061674629 @default.
• W2124238464 hasRelatedWork W2090738356 @default.
• W2124238464 hasRelatedWork W2408854117 @default.
• W2124238464 hasRelatedWork W2965806166 @default.
• W2124238464 hasRelatedWork W3002307457 @default.
• W2124238464 hasRelatedWork W3021723147 @default.
• W2124238464 hasRelatedWork W3103458680 @default.

• next