FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124248840> ?p ?o ?g. }

• W2124248840 endingPage "696" @default.
• W2124248840 startingPage "686" @default.
• W2124248840 abstract "Summary It has been estimated that chronic infections with viruses, bacteria and parasites contribute to 17·8% of the global burden of cancer, although only a relatively small proportion of the infection‐related cancers can be attributed to helminth infections. These are important because of the high number of people who are exposed or infected worldwide. Carcinogenesis associated with helminth infections is a complex process, which may involve several different mechanisms, but chronic inflammation is a key feature. Host immune responses and immunopathological processes mediate inflammatory responses and any failure in the control of the immunological components involved in this response can lead to chronic inflammation. This may generate a microenvironment that might be conducive to the initiation and development of cancer. Inflammatory cells generate free radicals and nitrogen species, which can oxidize and damage DNA and lead to genetic instabilities and malignant transformation. Physical damage caused by the parasites, their eggs or secreted products leads to restorative hyperplasia of the damaged tissue. This may promote the propagation of cells, in which genotoxic damage and pre‐malignant change has taken place. Three helminth infections have been classified as definitely carcinogenic to humans (group 1 carcinogens), namely Schistosoma haematobium , which is associated with cancer of the urinary bladder and the food‐borne liver flukes Clonorchis sinensis and Opisthorchis viverrini associated with cholangiocarcinoma of the liver. Reducing the level of infection and the risk of getting (re)infected will reduce the risk of cancer development later in life. Helminth infections are thus a preventable cause of cancer, emphasizing the need for sustainable helminth control in endemic areas coupled with health education, especially in relation to food‐borne liver fluke infections." @default.
• W2124248840 created "2016-06-24" @default.
• W2124248840 creator A5059206108 @default.
• W2124248840 creator A5066961810 @default.
• W2124248840 date "2009-10-07" @default.
• W2124248840 modified "2023-09-30" @default.
• W2124248840 title "Helminths and malignancy" @default.
• W2124248840 cites W10740861 @default.
• W2124248840 cites W1488389671 @default.
• W2124248840 cites W1507585765 @default.
• W2124248840 cites W1565513363 @default.
• W2124248840 cites W1574822285 @default.
• W2124248840 cites W1764920507 @default.
• W2124248840 cites W1963609812 @default.
• W2124248840 cites W1964199023 @default.
• W2124248840 cites W1964488322 @default.
• W2124248840 cites W1965037168 @default.
• W2124248840 cites W1968259100 @default.
• W2124248840 cites W1976977308 @default.
• W2124248840 cites W1978443737 @default.
• W2124248840 cites W1982464194 @default.
• W2124248840 cites W1983182756 @default.
• W2124248840 cites W1983287671 @default.
• W2124248840 cites W1987510192 @default.
• W2124248840 cites W1989347187 @default.
• W2124248840 cites W1990057233 @default.
• W2124248840 cites W1990929640 @default.
• W2124248840 cites W1994216489 @default.
• W2124248840 cites W1995316103 @default.
• W2124248840 cites W1996396767 @default.
• W2124248840 cites W1997851561 @default.
• W2124248840 cites W1998380437 @default.
• W2124248840 cites W1999425287 @default.
• W2124248840 cites W1999928502 @default.
• W2124248840 cites W2000760794 @default.
• W2124248840 cites W2001445043 @default.
• W2124248840 cites W2002400614 @default.
• W2124248840 cites W2004895340 @default.
• W2124248840 cites W2005051701 @default.
• W2124248840 cites W2005557329 @default.
• W2124248840 cites W2005790972 @default.
• W2124248840 cites W2007043238 @default.
• W2124248840 cites W2008487299 @default.
• W2124248840 cites W2011453409 @default.
• W2124248840 cites W2011743880 @default.
• W2124248840 cites W2011901371 @default.
• W2124248840 cites W2012369608 @default.
• W2124248840 cites W2012956445 @default.
• W2124248840 cites W2015999931 @default.
• W2124248840 cites W2016769463 @default.
• W2124248840 cites W2017549776 @default.
• W2124248840 cites W2017787490 @default.
• W2124248840 cites W2018740966 @default.
• W2124248840 cites W2022148808 @default.
• W2124248840 cites W2023107417 @default.
• W2124248840 cites W2023354876 @default.
• W2124248840 cites W2023953073 @default.
• W2124248840 cites W2024921507 @default.
• W2124248840 cites W2027057932 @default.
• W2124248840 cites W2028388355 @default.
• W2124248840 cites W2029500518 @default.
• W2124248840 cites W2031054947 @default.
• W2124248840 cites W2031547300 @default.
• W2124248840 cites W2032461734 @default.
• W2124248840 cites W2033659139 @default.
• W2124248840 cites W2035583858 @default.
• W2124248840 cites W2035785908 @default.
• W2124248840 cites W2039745983 @default.
• W2124248840 cites W2039994523 @default.
• W2124248840 cites W2041509997 @default.
• W2124248840 cites W2041689149 @default.
• W2124248840 cites W2048212955 @default.
• W2124248840 cites W2048388381 @default.
• W2124248840 cites W2048730047 @default.
• W2124248840 cites W2049050324 @default.
• W2124248840 cites W2051765493 @default.
• W2124248840 cites W2053923770 @default.
• W2124248840 cites W2054156078 @default.
• W2124248840 cites W2054566387 @default.
• W2124248840 cites W2058803223 @default.
• W2124248840 cites W2061235114 @default.
• W2124248840 cites W2061703004 @default.
• W2124248840 cites W2073525854 @default.
• W2124248840 cites W2073814301 @default.
• W2124248840 cites W2076259033 @default.
• W2124248840 cites W2080926419 @default.
• W2124248840 cites W2090010249 @default.
• W2124248840 cites W2092823617 @default.
• W2124248840 cites W2102432217 @default.
• W2124248840 cites W2105893493 @default.
• W2124248840 cites W2108250804 @default.
• W2124248840 cites W2110906888 @default.
• W2124248840 cites W2110929110 @default.
• W2124248840 cites W2111006735 @default.
• W2124248840 cites W2111619925 @default.
• W2124248840 cites W2113470587 @default.
• W2124248840 cites W2115892230 @default.
• W2124248840 cites W2116263727 @default.

• next