Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124327952> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2124327952 endingPage "349" @default.
- W2124327952 startingPage "345" @default.
- W2124327952 abstract "Abstract Both bone marrow and circulating megakaryocytes may produce platelets. Changes in number and properties of the circulating megakaryocytes in cardiac diseases may provide information about thrombopoiesis in these disease states. Circulating megakaryocytes were obtained by retrograde aspiration through wedged pulmonary artery catheters from patients without cardiac abnormalities, patients with cardiac diseases and patients with disorders known to affect the megakaryocyte-platelet axis or marrowblood barrier. Their number, ploidy distribution and expression of the β1-integrin adhesion antigens were estimated. We found evidence for an increased number of circulating megakaryocytes during acute myocardial infarction and in patients with triple vessel disease. A significantly higher proportion of circulating megakaryocytes obtained within 60 h after acute myocardial infarction, expressed CDw49b (α-chain of VLA2), CDw49e (α-chain of VLA5), and CDw49f (α-chain of VLA6) compared to megakaryocytes of patients without cardiac diseases. In myocardial infarction the increase in number of circulating megakaryocytes together with the higher proportion that expressed the β1-integrin adhesion antigens favour the hypothesis that these megakaryocytes are acutely released from the bone marrow. This could reflect either a selective response to an increased demand for circulating platelets or be the result of an aselective mechanism resulting from damage to the marrow-blood barrier following the acute infarction or thrombolytic therapy administered." @default.
- W2124327952 created "2016-06-24" @default.
- W2124327952 creator A5006966014 @default.
- W2124327952 creator A5040217641 @default.
- W2124327952 creator A5066783292 @default.
- W2124327952 creator A5072170382 @default.
- W2124327952 creator A5083596009 @default.
- W2124327952 date "1994-05-01" @default.
- W2124327952 modified "2023-10-18" @default.
- W2124327952 title "Circulating human megakaryocytes in cardiac diseases" @default.
- W2124327952 cites W1973218728 @default.
- W2124327952 cites W1974777806 @default.
- W2124327952 cites W1980379518 @default.
- W2124327952 cites W1980478112 @default.
- W2124327952 cites W1990329455 @default.
- W2124327952 cites W2005410473 @default.
- W2124327952 cites W2032217476 @default.
- W2124327952 cites W2054475676 @default.
- W2124327952 cites W2086628106 @default.
- W2124327952 cites W2092884940 @default.
- W2124327952 cites W2163147532 @default.
- W2124327952 cites W2246953630 @default.
- W2124327952 cites W2313098007 @default.
- W2124327952 cites W2406013318 @default.
- W2124327952 doi "https://doi.org/10.1111/j.1365-2362.1994.tb01095.x" @default.
- W2124327952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8088311" @default.
- W2124327952 hasPublicationYear "1994" @default.
- W2124327952 type Work @default.
- W2124327952 sameAs 2124327952 @default.
- W2124327952 citedByCount "6" @default.
- W2124327952 countsByYear W21243279522012 @default.
- W2124327952 countsByYear W21243279522014 @default.
- W2124327952 countsByYear W21243279522020 @default.
- W2124327952 countsByYear W21243279522021 @default.
- W2124327952 countsByYear W21243279522022 @default.
- W2124327952 countsByYear W21243279522023 @default.
- W2124327952 crossrefType "journal-article" @default.
- W2124327952 hasAuthorship W2124327952A5006966014 @default.
- W2124327952 hasAuthorship W2124327952A5040217641 @default.
- W2124327952 hasAuthorship W2124327952A5066783292 @default.
- W2124327952 hasAuthorship W2124327952A5072170382 @default.
- W2124327952 hasAuthorship W2124327952A5083596009 @default.
- W2124327952 hasConcept C109159458 @default.
- W2124327952 hasConcept C126322002 @default.
- W2124327952 hasConcept C142724271 @default.
- W2124327952 hasConcept C164705383 @default.
- W2124327952 hasConcept C203014093 @default.
- W2124327952 hasConcept C2776958478 @default.
- W2124327952 hasConcept C2777798775 @default.
- W2124327952 hasConcept C2779705218 @default.
- W2124327952 hasConcept C2780007613 @default.
- W2124327952 hasConcept C28328180 @default.
- W2124327952 hasConcept C500558357 @default.
- W2124327952 hasConcept C54355233 @default.
- W2124327952 hasConcept C71924100 @default.
- W2124327952 hasConcept C86803240 @default.
- W2124327952 hasConcept C89560881 @default.
- W2124327952 hasConceptScore W2124327952C109159458 @default.
- W2124327952 hasConceptScore W2124327952C126322002 @default.
- W2124327952 hasConceptScore W2124327952C142724271 @default.
- W2124327952 hasConceptScore W2124327952C164705383 @default.
- W2124327952 hasConceptScore W2124327952C203014093 @default.
- W2124327952 hasConceptScore W2124327952C2776958478 @default.
- W2124327952 hasConceptScore W2124327952C2777798775 @default.
- W2124327952 hasConceptScore W2124327952C2779705218 @default.
- W2124327952 hasConceptScore W2124327952C2780007613 @default.
- W2124327952 hasConceptScore W2124327952C28328180 @default.
- W2124327952 hasConceptScore W2124327952C500558357 @default.
- W2124327952 hasConceptScore W2124327952C54355233 @default.
- W2124327952 hasConceptScore W2124327952C71924100 @default.
- W2124327952 hasConceptScore W2124327952C86803240 @default.
- W2124327952 hasConceptScore W2124327952C89560881 @default.
- W2124327952 hasIssue "5" @default.
- W2124327952 hasLocation W21243279521 @default.
- W2124327952 hasLocation W21243279522 @default.
- W2124327952 hasOpenAccess W2124327952 @default.
- W2124327952 hasPrimaryLocation W21243279521 @default.
- W2124327952 hasRelatedWork W1966851715 @default.
- W2124327952 hasRelatedWork W1976789781 @default.
- W2124327952 hasRelatedWork W1978942285 @default.
- W2124327952 hasRelatedWork W1994540414 @default.
- W2124327952 hasRelatedWork W2059903063 @default.
- W2124327952 hasRelatedWork W2332253499 @default.
- W2124327952 hasRelatedWork W2593811684 @default.
- W2124327952 hasRelatedWork W2851093530 @default.
- W2124327952 hasRelatedWork W3103959747 @default.
- W2124327952 hasRelatedWork W4248876388 @default.
- W2124327952 hasVolume "24" @default.
- W2124327952 isParatext "false" @default.
- W2124327952 isRetracted "false" @default.
- W2124327952 magId "2124327952" @default.
- W2124327952 workType "article" @default.