Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124332129> ?p ?o ?g. }
- W2124332129 endingPage "1446" @default.
- W2124332129 startingPage "1441" @default.
- W2124332129 abstract "Three Candida albicans strains were tested in the presence of 17-beta-estradiol (10-6 M and 10-9 M) for increased growth and for enhanced survival during incubation at nonpermissive temperatures. All 3 test organisms showed increased growth in the presence of estradiol compared with estrogen-free controls. Likewise, all 3 strains, when treated with estradiol, survived incubation at 48 degrees C better than did controls. Cytoplasmic extracts were probed with an anti-hsp90 antibody, and results suggested that intracellular hsp90 was up-regulated in the presence of 10-9 M 17-beta-estradiol. The results were confirmed by reverse-transcriptase polymerase chain reaction with primers specific for C. albicans hsp90. A kinetic study revealed that peak hsp90 expression occurred within 2 h of exposure to 17-beta-estradiol. In addition, estrogen increased the amount of cdr1 (Candida multidrug resistance) mRNA compared with cells not treated with estrogen. Coumarin and phenol also up-regulated hsp90 and cdr1 mRNAs, indicating that the estrogen-sensing and -response systems in C. albicans may lack specificity." @default.
- W2124332129 created "2016-06-24" @default.
- W2124332129 creator A5001528771 @default.
- W2124332129 creator A5016861046 @default.
- W2124332129 creator A5018585684 @default.
- W2124332129 creator A5056436243 @default.
- W2124332129 date "2000-04-01" @default.
- W2124332129 modified "2023-09-27" @default.
- W2124332129 title "Estrogen Effects on<i>Candida albicans:</i>A Potential Virulence‐Regulating Mechanism" @default.
- W2124332129 cites W193440392 @default.
- W2124332129 cites W1956379070 @default.
- W2124332129 cites W1973594359 @default.
- W2124332129 cites W2003326305 @default.
- W2124332129 cites W2005088750 @default.
- W2124332129 cites W2040927609 @default.
- W2124332129 cites W2046385725 @default.
- W2124332129 cites W2063865658 @default.
- W2124332129 cites W2071482962 @default.
- W2124332129 cites W2078494827 @default.
- W2124332129 cites W2089819283 @default.
- W2124332129 cites W2091055810 @default.
- W2124332129 cites W2091189600 @default.
- W2124332129 cites W2095906727 @default.
- W2124332129 cites W2098563304 @default.
- W2124332129 cites W2099992860 @default.
- W2124332129 cites W2140963713 @default.
- W2124332129 cites W2146102239 @default.
- W2124332129 cites W2157383239 @default.
- W2124332129 cites W2158856360 @default.
- W2124332129 cites W2159209506 @default.
- W2124332129 cites W2170090443 @default.
- W2124332129 cites W2411504206 @default.
- W2124332129 cites W60975216 @default.
- W2124332129 cites W2471801749 @default.
- W2124332129 doi "https://doi.org/10.1086/315406" @default.
- W2124332129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10762574" @default.
- W2124332129 hasPublicationYear "2000" @default.
- W2124332129 type Work @default.
- W2124332129 sameAs 2124332129 @default.
- W2124332129 citedByCount "81" @default.
- W2124332129 countsByYear W21243321292012 @default.
- W2124332129 countsByYear W21243321292013 @default.
- W2124332129 countsByYear W21243321292014 @default.
- W2124332129 countsByYear W21243321292015 @default.
- W2124332129 countsByYear W21243321292016 @default.
- W2124332129 countsByYear W21243321292017 @default.
- W2124332129 countsByYear W21243321292018 @default.
- W2124332129 countsByYear W21243321292019 @default.
- W2124332129 countsByYear W21243321292020 @default.
- W2124332129 countsByYear W21243321292021 @default.
- W2124332129 countsByYear W21243321292022 @default.
- W2124332129 crossrefType "journal-article" @default.
- W2124332129 hasAuthorship W2124332129A5001528771 @default.
- W2124332129 hasAuthorship W2124332129A5016861046 @default.
- W2124332129 hasAuthorship W2124332129A5018585684 @default.
- W2124332129 hasAuthorship W2124332129A5056436243 @default.
- W2124332129 hasBestOaLocation W21243321291 @default.
- W2124332129 hasConcept C104317684 @default.
- W2124332129 hasConcept C134018914 @default.
- W2124332129 hasConcept C145081991 @default.
- W2124332129 hasConcept C153911025 @default.
- W2124332129 hasConcept C156719811 @default.
- W2124332129 hasConcept C25642318 @default.
- W2124332129 hasConcept C2777164284 @default.
- W2124332129 hasConcept C2780917455 @default.
- W2124332129 hasConcept C49105822 @default.
- W2124332129 hasConcept C55493867 @default.
- W2124332129 hasConcept C79879829 @default.
- W2124332129 hasConcept C86803240 @default.
- W2124332129 hasConcept C89423630 @default.
- W2124332129 hasConceptScore W2124332129C104317684 @default.
- W2124332129 hasConceptScore W2124332129C134018914 @default.
- W2124332129 hasConceptScore W2124332129C145081991 @default.
- W2124332129 hasConceptScore W2124332129C153911025 @default.
- W2124332129 hasConceptScore W2124332129C156719811 @default.
- W2124332129 hasConceptScore W2124332129C25642318 @default.
- W2124332129 hasConceptScore W2124332129C2777164284 @default.
- W2124332129 hasConceptScore W2124332129C2780917455 @default.
- W2124332129 hasConceptScore W2124332129C49105822 @default.
- W2124332129 hasConceptScore W2124332129C55493867 @default.
- W2124332129 hasConceptScore W2124332129C79879829 @default.
- W2124332129 hasConceptScore W2124332129C86803240 @default.
- W2124332129 hasConceptScore W2124332129C89423630 @default.
- W2124332129 hasIssue "4" @default.
- W2124332129 hasLocation W21243321291 @default.
- W2124332129 hasLocation W21243321292 @default.
- W2124332129 hasOpenAccess W2124332129 @default.
- W2124332129 hasPrimaryLocation W21243321291 @default.
- W2124332129 hasRelatedWork W2128291007 @default.
- W2124332129 hasRelatedWork W2298392156 @default.
- W2124332129 hasRelatedWork W2625463353 @default.
- W2124332129 hasRelatedWork W2888350538 @default.
- W2124332129 hasRelatedWork W2941029072 @default.
- W2124332129 hasRelatedWork W2946449973 @default.
- W2124332129 hasRelatedWork W3092085651 @default.
- W2124332129 hasRelatedWork W3104380876 @default.
- W2124332129 hasRelatedWork W4297252087 @default.
- W2124332129 hasRelatedWork W4300690271 @default.