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• W2124346064 abstract "ABSTRACT Staphylococcus aureus is a common pathogen associated with nosocomial infections. It can persist in clinical settings and gain increased resistance to antimicrobial agents through biofilm formation. We have found that alpha-toxin, a secreted, multimeric, hemolytic toxin encoded by the hla gene, plays an integral role in biofilm formation. The hla mutant was unable to fully colonize plastic surfaces under both static and flow conditions. Based on microscopy studies, we propose that alpha-hemolysin is required for cell-to-cell interactions during biofilm formation." @default.
• W2124346064 created "2016-06-24" @default.
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• W2124346064 date "2003-05-15" @default.
• W2124346064 modified "2023-10-02" @default.
• W2124346064 title "Alpha-Toxin Is Required for Biofilm Formation by <i>Staphylococcus aureus</i>" @default.
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• W2124346064 doi "https://doi.org/10.1128/jb.185.10.3214-3217.2003" @default.
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