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• W2124354523 abstract "Background : In order to improve MRI volumetry of hippocampus, we obtained the Longitudinal Regional Volume Curve (LRVC) of hippocampi and compared the sensitivity of LRVC with those of conventional hippocampal volume- tries (total and regional) in temporal lobe epilepsy (TLE). Methods : Thirty-eight normal subjects and 24 TLE patients were included in this study. The pathology of all patients showed hippocampal sclerosis. The volume of the hippocam - pus was measured by a manual tracing in 3 mm-thickness coronal MRI slices perpendicular to the long axis of the hip - pocampus and a three-dimensional reconstruction. Total volume and regional volumes (anterior, middle, and posterior 1/3) of the right and left hippocampi were measured. Then, the focal hippocampal volume of each of the coronal slices (3 mm) was plotted in a X-Y graph to obtain LRVC. The presence and pattern of HA were determined in LRVC. Results : The mean volume of right hippocampus (2512±629 mm 3 ) was bigger than that of the left one (2262.6±563.2 mm 3 ) in normal subjects. The normal range of right-left total volume difference was 3.6~495.2 mm 3 . The sensitivities of conventional volumetry, regional volumetry, and LRVC were 66.7%, 75%, and 83.3%, respectively. Eleven patients showed diffuse HA (11/20, 55.0%) and nine had focal HA (9/20, 45.0%). In focal HA, the middle and posterior HA were more frequent (6/9, 66.7%) than anterior HA. Conclusions : LRVC improved the sensitivity of MRI volumetry in detecting hippocampal sclerosis and could reveal the pattern (diffuse or focal) of HA. J Korean Neurol Assoc 19(2):125~131, 2001" @default.
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• W2124354523 date "2001-01-01" @default.
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• W2124354523 title "Regional MRI Volumetry and Longitudinal Regional Volume Curve for Detecting Hippocampal Sclerosis in Temporal Lobe Epilepsy" @default.
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