Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124383208> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2124383208 endingPage "3180" @default.
- W2124383208 startingPage "3175" @default.
- W2124383208 abstract "A histologic study was performed on the livers of wild-type (WT), severe combined immunodeficient (SCID), hydrocortisone acetate (HC)-treated WT, and HC-treated SCID mice infected intravenously with 10(5) CFU of Mycobacterium bovis BCG. It was found that infection progressed faster in SCID mice than in WT mice and that HC treatment caused exacerbation of infection in both types of mice. In all cases infection in the liver was confined to granulomas that were populated predominantly by macrophages. Higher levels of infection in HC-treated SCID mice, but not HC-treated WT mice, were associated with extensive infection and destruction of parenchymal cells at the margins of granulomas. The results indicate that in the absence of T-cell-mediated immunity and of HC-sensitive T-cell-independent defense mechanisms, macrophages are incapable of restricting BCG growth and of confining infection to their cytoplasm. Consequently, BCG bacilli are released into the extracellular environment, where they are ingested by neighboring parenchymal cells." @default.
- W2124383208 created "2016-06-24" @default.
- W2124383208 creator A5007179531 @default.
- W2124383208 creator A5053391155 @default.
- W2124383208 creator A5060940826 @default.
- W2124383208 creator A5090093609 @default.
- W2124383208 date "2001-05-01" @default.
- W2124383208 modified "2023-09-26" @default.
- W2124383208 title "Extensive Mycobacterium bovis BCG Infection of Liver Parenchymal Cells in Immunocompromised Mice" @default.
- W2124383208 cites W1519063308 @default.
- W2124383208 cites W1597086056 @default.
- W2124383208 cites W1819840072 @default.
- W2124383208 cites W1967945767 @default.
- W2124383208 cites W2004005506 @default.
- W2124383208 cites W2021598397 @default.
- W2124383208 cites W2041697029 @default.
- W2124383208 cites W2064788322 @default.
- W2124383208 cites W2084564714 @default.
- W2124383208 cites W2086662036 @default.
- W2124383208 cites W2112522175 @default.
- W2124383208 cites W2115477132 @default.
- W2124383208 cites W2118757090 @default.
- W2124383208 cites W2131604051 @default.
- W2124383208 cites W2136888669 @default.
- W2124383208 cites W2157331909 @default.
- W2124383208 cites W2158035277 @default.
- W2124383208 cites W2165094248 @default.
- W2124383208 cites W57615383 @default.
- W2124383208 cites W649120216 @default.
- W2124383208 doi "https://doi.org/10.1128/iai.69.5.3175-3180.2001" @default.
- W2124383208 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/98274" @default.
- W2124383208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11292738" @default.
- W2124383208 hasPublicationYear "2001" @default.
- W2124383208 type Work @default.
- W2124383208 sameAs 2124383208 @default.
- W2124383208 citedByCount "8" @default.
- W2124383208 countsByYear W21243832082016 @default.
- W2124383208 crossrefType "journal-article" @default.
- W2124383208 hasAuthorship W2124383208A5007179531 @default.
- W2124383208 hasAuthorship W2124383208A5053391155 @default.
- W2124383208 hasAuthorship W2124383208A5060940826 @default.
- W2124383208 hasAuthorship W2124383208A5090093609 @default.
- W2124383208 hasBestOaLocation W21243832082 @default.
- W2124383208 hasConcept C142724271 @default.
- W2124383208 hasConcept C196822366 @default.
- W2124383208 hasConcept C203014093 @default.
- W2124383208 hasConcept C2777928079 @default.
- W2124383208 hasConcept C2777975735 @default.
- W2124383208 hasConcept C2778497218 @default.
- W2124383208 hasConcept C2779341262 @default.
- W2124383208 hasConcept C2781069245 @default.
- W2124383208 hasConcept C28406088 @default.
- W2124383208 hasConcept C59822182 @default.
- W2124383208 hasConcept C71924100 @default.
- W2124383208 hasConcept C86803240 @default.
- W2124383208 hasConcept C8891405 @default.
- W2124383208 hasConcept C89423630 @default.
- W2124383208 hasConcept C95444343 @default.
- W2124383208 hasConceptScore W2124383208C142724271 @default.
- W2124383208 hasConceptScore W2124383208C196822366 @default.
- W2124383208 hasConceptScore W2124383208C203014093 @default.
- W2124383208 hasConceptScore W2124383208C2777928079 @default.
- W2124383208 hasConceptScore W2124383208C2777975735 @default.
- W2124383208 hasConceptScore W2124383208C2778497218 @default.
- W2124383208 hasConceptScore W2124383208C2779341262 @default.
- W2124383208 hasConceptScore W2124383208C2781069245 @default.
- W2124383208 hasConceptScore W2124383208C28406088 @default.
- W2124383208 hasConceptScore W2124383208C59822182 @default.
- W2124383208 hasConceptScore W2124383208C71924100 @default.
- W2124383208 hasConceptScore W2124383208C86803240 @default.
- W2124383208 hasConceptScore W2124383208C8891405 @default.
- W2124383208 hasConceptScore W2124383208C89423630 @default.
- W2124383208 hasConceptScore W2124383208C95444343 @default.
- W2124383208 hasIssue "5" @default.
- W2124383208 hasLocation W21243832081 @default.
- W2124383208 hasLocation W21243832082 @default.
- W2124383208 hasLocation W21243832083 @default.
- W2124383208 hasLocation W21243832084 @default.
- W2124383208 hasOpenAccess W2124383208 @default.
- W2124383208 hasPrimaryLocation W21243832081 @default.
- W2124383208 hasRelatedWork W1978162700 @default.
- W2124383208 hasRelatedWork W1997276814 @default.
- W2124383208 hasRelatedWork W2057948995 @default.
- W2124383208 hasRelatedWork W2130915823 @default.
- W2124383208 hasRelatedWork W2131926746 @default.
- W2124383208 hasRelatedWork W2164136796 @default.
- W2124383208 hasRelatedWork W3017822181 @default.
- W2124383208 hasRelatedWork W3032124789 @default.
- W2124383208 hasRelatedWork W3032210197 @default.
- W2124383208 hasRelatedWork W573847062 @default.
- W2124383208 hasVolume "69" @default.
- W2124383208 isParatext "false" @default.
- W2124383208 isRetracted "false" @default.
- W2124383208 magId "2124383208" @default.
- W2124383208 workType "article" @default.