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- W2124388214 abstract "For unknown reasons, the incidence of oesophageal adenocarcinoma is rising rapidly in the UK 1 Reed PI Changing pattern of oesophageal cancer. Lancet. 1991; 338: 178 Abstract Scopus (46) Google Scholar and the USA. 2 Hesketh PJ Clapp RW Doos WG Spechler SJ The increasing frequency of adenocarcinoma of the esophagus. Cancer. 1989; 64: 526-530 Crossref PubMed Scopus (192) Google Scholar In particular, in scotland, the incidence of oesophageal adenocarcinoma has risen from 3·0 per 100 000 in 1976 (age-standardised rate) to 4·6 per 100 000 in 1989. 3 McKinney PA Sharp L Macfarlane GJ Muir CS Oesophageal and gastric cancer in scotland 1960–90. Br J Cancer. 1995; 71: 411-415 Crossref PubMed Scopus (71) Google Scholar Barrett's oesophagus is a premalignant metaplastic change in the lining of the distal oesophagus and is the only recognised risk factor for the development of oesophageal adenocarcinoma conferring a 30–125 times increased risk. It might be suspected that this increase of oesophageal adenocarcinoma is mirrored by a similar rise in the incidence of Barrett's oesophagus, however, currently there are no data to substantiate this. We have studied the incidence of endoscopically diagnosed Barrett's oesophagus in Tayside to determine whether there is an increasing incidence of Barrett's oesophagus in our population." @default.
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- W2124388214 date "1997-09-01" @default.
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- W2124388214 title "Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology?" @default.
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- W2124388214 doi "https://doi.org/10.1016/s0140-6736(05)63269-2" @default.
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